the coronary slow flow phenomenon (csfp) is characterized by a delayed coronary blood flow in the absence of an obstructive coronary artery disease. although the relation between the csfp and myocardial ischemia has been reported previously, there is no knowledge about the relationship between the csfp and the conduction system disorder. in this case report, we describe a patient with the csfp ...

conclusions in most cases, the conus artery can be visualized in cardiac ct. a description of the conus artery should be a part of the standard clinical coronary ct angiography description. objectives to examine whether it is possible to visualize the conus artery in multi-slice computed tomography (ct). patients and methods in 79 consecutive patients (aged 56 ± 12.9 years; 13 women), 64-slice ...

Oxidized LDLs (Ox-LDLs) inhibit endothelium-dependent dilation of isolated conduit arteries in a manner comparable to the impairment demonstrated in atherosclerotic vessels. However, it is not known whether the microvessels, which do not develop atherosclerotic lesions, are susceptible to Ox-LDL. Since endothelial release of NO plays an important role in vasodilation and since its dysfunction a...

In this paper, the problem of large pure bending deformations of membrane is considered. The membrane is a sector of torus with a closed cross-section. This membrane is called a curved tube for short. We consider the homogenous, incompressible, isotropic and hyperelastic material. The external load is a constant pressure and bending couples acting at the edges. The equilibrium equations reduce ...

Previous studies show that agonist-induced, nitric oxide (NO)-mediated arteriolar dilations are greater in female than in male rats. Thus we hypothesized that flow-dependent arteriolar dilation, which is in part mediated by NO, is also greater in females than in males. Gracilis muscle arterioles from 12-wk-old female and male Wistar rats were isolated, cannulated, and pressurized. At 80 mmHg of...

We investigated the effect of atorvastatin on cyclooxygenase (COX) contribution to endothelial dysfunction in spontaneously hypertensive rat (SHR) mesenteric resistance arteries. Atorvastatin (10 mg/kg per day, oral gavage) or its vehicle was administered for 2 weeks to male SHR or Wistar-Kyoto rats. Endothelial function of mesenteric arteries was assessed by pressurized myograph. In Wistar-Kyo...

Lymphatic muscle (LM) is widely considered to be a type of vascular smooth muscle, even though LM cells uniquely express contractile proteins from both smooth muscle and cardiac muscle. We tested the hypothesis that LM exhibits an unloaded maximum shortening velocity (Vmax) intermediate between that of smooth muscle and cardiac muscle. Single lymphatic vessels were dissected from the rat mesent...

Studies were performed to determine the significance of temporal variation in vascular smooth muscle Ca(2+) signaling during acute arteriolar myogenic constriction and, in particular, the importance of the stretch-induced intracellular Ca(2+) concentration ([Ca(2+)](i)) transient in attaining a steady-state mechanical response. Rat cremaster arterioles (diameter approximately 100 microm) were d...