OBJECTIVE Preterm infants are exposed to multiple painful procedures in the neonatal intensive care unit (NICU) during a period of rapid brain development. Our aim was to examine relationships between procedural pain in the NICU and early brain development in very preterm infants. METHODS Infants born very preterm (N=86; 24-32 weeks gestational age) were followed prospectively from birth, and...

BACKGROUND The development of respiratory distress syndrome (RDS) is closely related to fetal immaturity, although the participation of inflammatory mechanisms also seems to be likely. We previously reported high interleukin-10 (IL-10) levels in cord blood from preterm infants. In the present study, we investigate the possible role of IL-10 and IL-12 in preterm newborns with RDS, a disease that...

purpose: to determine the frequency of congenital nasolacrimal duct obstruction (cnldo) in premature newborns and its correlation with gestational age (ga), sex, family history and chronological age. methods: this study was performed on infants who were referred for retinopathy of prematurity from 2002 to 2003. cases of cnldo were visited again three and six months later. results: this study wa...

The study aimed to determine the presence of a relationship between prenatal exposure potential risk factors and development necrotizing enterocolitis (NEC) in premature infants. Materials Methods: clinical data 99 mother-newborn couples diagnosed with Bell’s stage IIA NEC comparable comparison group were studied. characteristics main compared control using Student’s t-test. To assess severity ...

BACKGROUND Breastfeeding of premature babies. AIM To describe breastfeeding in premature babies with very low birth weight (VLBW) and its association with the oral motor system (OMS) and with maternal-child bonding. METHOD A cross-sectional study with 48 VLBW premature babies. An interview with the mothers, as well as the evaluation of the newborns' OMS and signs of attachment was performed...

OBJECTIVE To investigate prevalence of invasive candidiasis in a Neonatal Intensive Care Unit and to evaluate oral diseases and Candida spp. colonization in low birth weight preterm newborns. METHODS A descriptive epidemiological study performed in two stages. First, prevalence of candidiasis was analyzed in a database of 295 preterm patients admitted to hospital for over 10 days and birth we...

Ibuprofen is used for the closure of ductus arteriosus either intravenously or enterally. Although intraventricular hemorrhage, necrotizing enterocolitis, bronchopulmonary dysplasia, transient renal failure, oliguria, hyponatremia and thrombocytopenia are reported complications during or after ibuprofen treatment, gastrointestinal bleeding, to our knowledge, has not been reported previously. We...

  Introduction :Jaundice is the most common cause of hospitalization of infants in the first month of life. Delivery and maternal and neonatal risk factors may affect the progression of complications of jaundice. This study aimed to investigate the problems of pregnancy and delivery in neonates with jaundice. Methods: This descriptive study was performed on 2796 full term 3 to 29 day infants w...

During the last two decades, dramatic improvement in survival of newborns, especially the extremely premature group, resulted from major advances such as antenatal steroids and surfactant, as well as from many other less dramatic improvements in care. As fewer babies died of respiratory failure and smaller babies survive, infection has become an increasingly important cause of mortality and mor...

Persistent pulmonary interstitial emphysema is a chronic disease reported in mechanically ventilated premature newborns. We describe a case of localized persistent pulmonary interstitial emphysema in a preterm infant without mechanical ventilation but on continuous positive airway pressure using nasal prongs. The condition resolved without surgery.