Gastric duplication cyst (GDC) in an adult can have several clinical presentations. A review of the literature showed previously reported cases of GDC presenting as pancreatic pseudocyst or with greatly raised concentrations of carbohydrate antigen 19-9 (CA 19-9). It is often difficult to discriminate GDC from pancreatic cystic tumour, in particular pancreatic mucinous cystadenoma, in which con...

The changes in lipid profile have long been associated with cancer because lipids play a key role in maintenance of cell integrity. Lipids are the major cell membrane components essential for various biological functions including cell growth and division of normal and malignant tissues. Lower blood lipids have been associated with the etiology of breast and colorectal cancer, and relation has ...

B3 lesions represent 3–10% of the histologically assessed lesions in mammography screening. They comprise different histopathological entities which provide benign histology, but are either known to show heterogeneity or to have an increased (albeit low) risk of associated malignancy, e.g. FEA, ADH, lobular neoplasia (LN), papillary lesions, radial scar, and phyllodes tumor. With regard to the ...

Background: Cervical cancer is one of the main reasons death in developing countries around world, with an incidence sixty-one percent females, so it important to detect precancerous lesion decrease morbidity and mortality rates due cervical cancer.

Notwithstanding the definite aetiopathogenetic path of certain diseases, the relationship between Helicobacter pylori (H. pylori) and Barrett’s esophagus (BE), a condition that increases the risk for dysplasia and consequently adenocarcinoma of the distal esophagus and esophagogastric junction, remains uncertain. This paper reviews the current scientific literature with emphasis on the protecti...

A 73-year-old man with short segmental Barrett's esophagus underwent esophagoscopy, and a slightly depressed, discolored lesion was found on the anterior wall of the lower esophagus. Under a provisional diagnosis of differentiated adenocarcinoma without local lymph node metastasis, endoscopic submucosal dissection (ESD) was carried out. En bloc resection with tumor-free lateral/basal margins wa...

Dear Editor, A b o u t 5 m i l l i o n p e o p l e i n I n d i a h ave o r a l submucous fibrosis and recent data suggest a male predominance. Age group between second and third decade is commonly involved. Risk of malignant transformation ranges from 7% to 30%. Restricted mouth opening in oral submucous fibrosis makes examination and early diagnosis of cancer difficult. Medical management is t...

Submucous fibrosis (SMF) an important precancerous condition occurs almost exclusively in Indians but cases have been reported from several countries throughout the world. The causes of SMF are unknown and there is no known treatment for it. Chillies, tobacco use, vitamin deficiencies and betel quid chewing have been implicated. Ramanathan is of the view that SMF seems to be the Asian version o...

OBJECTIVE To investigate whether microsatellite instability (MSI) of gastric cancer and precancerous lesions were existed and its effect. METHODS Laser microdissection was used. Gastric, intestinal metaplasia, dysplasia and normal mucosa were collected respectively. Five microsatellite loci were selected and MSI was detected by denaturing high-performance liquid chromatography. RESULTS In t...