نتایج جستجو برای: pre implantation embryo

تعداد نتایج: 429694  

2014
Naguib Salleh

Prostaglandins (PGs), derivatives of arachidonic acid, play an indispensable role in embryo implantation. PGs have been reported to participate in the increase in vascular permeability, stromal decidualization, blastocyst growth and development, leukocyte recruitment, embryo transport, trophoblast invasion, and extracellular matrix remodeling during implantation. Deranged PGs syntheses and acti...

2016
Mubeen Goolam Antonio Scialdone Sarah J.L. Graham Iain C. Macaulay Agnieszka Jedrusik Anna Hupalowska Thierry Voet John C. Marioni Magdalena Zernicka-Goetz

The major and essential objective of pre-implantation development is to establish embryonic and extra-embryonic cell fates. To address when and how this fundamental process is initiated in mammals, we characterize transcriptomes of all individual cells throughout mouse pre-implantation development. This identifies targets of master pluripotency regulators Oct4 and Sox2 as being highly heterogen...

2014
Ivan Bedzhov Sarah J. L. Graham Chuen Yan Leung Magdalena Zernicka-Goetz

A critical point in mammalian development is when the early embryo implants into its mother's uterus. This event has historically been difficult to study due to the fact that it occurs within the maternal tissue and therefore is hidden from view. In this review, we discuss how the mouse embryo is prepared for implantation and the molecular mechanisms involved in directing and coordinating this ...

2016
Pierre Osteil Anaïs Moulin Claire Santamaria Thierry Joly Luc Jouneau Maxime Aubry Yann Tapponnier Catherine Archilla Barbara Schmaltz-Panneau Jérôme Lecardonnel Harmonie Barasc Nathalie Mouney-Bonnet Clémence Genthon Alain Roulet Cécile Donnadieu Hervé Acloque Elen Gocza Véronique Duranthon Marielle Afanassieff Pierre Savatier

Conventional rabbit embryonic stem cell (ESC) lines are derived from the inner cell mass (ICM) of pre-implantation embryos using methods and culture conditions that are established for primate ESCs. In this study, we explored the capacity of the rabbit ICM to give rise to ESC lines using conditions similar to those utilized to generate naive ESCs in mice. On single-cell dissociation and culture...

Journal: :journal of reproduction and infertility 0

the success rate of reproductive treatment methods depends on many different factors. the most important and discussed ones in the literature are maternal age, the causes of infertility, the ovarian response to stimulation, the influence of the male factor and sperm quality, embryo quality and the various uterine pathologies. some couples fail repeatedly after transferring good quality embryos ...

2017
Marjaneh Kayssan Mahrokh Dolatian Reza Omani Samani Saman Maroufizadeh

OBJECTIVE After the introduction of assisted reproductive techniques, human embryos were officially introduced into laboratories and now thousands of them are cryopreserved in such settings. Embryonic stem cells and the future application of such cells in the treatment of disease opened the door to further research on human embryos. These developments raise many ethical issues, some of which ha...

Journal: :international journal of reproductive biomedicine 0
mohammad ebrahim parsanezhad nasrin dadras najmeh maharlouei leila neghahban peghah keramati madihe amini

background: unexplained infertility is still a challenging issue as to its causes, appropriate management and treatment. evidence implicates early embryopathy or implantation failure as likely causes. objective: this study aims to investigate the effect of local endometrial injury on pregnancy rate in selected unexplained infertile patients. materials and methods: this was a randomized clinical...

Journal: :Development 2012
Chanchao Lorthongpanich Tham Puay Yoke Doris Vachiranee Limviphuvadh Barbara B Knowles Davor Solter

The inside-outside model has been invoked to explain cell-fate specification of the pre-implantation mammalian embryo. Here, we investigate whether cell-cell interaction can influence the fate specification of embryonic blastomeres by sequentially separating the blastomeres in two-cell stage mouse embryos and continuing separation after each cell division throughout pre-implantation development...

Conaghan J Fischer E

Background: Vitrification and warming of blastocysts is an established procedure for the preservation of embryos during IVF. Vitrification is so successful that it allows for elective single embryo transfer (eSET) to be performed routinely, since the frozen embryos will be available with high implantation potential if the fresh embryo fails. Comprehensive chromosome screening (CCS) is also a pr...

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