BACKGROUND Oxidative stress, inducing cardiomyocyte apoptosis or myocardial ischemia, is the major denominator of many cardiac diseases. In this study, we intended to explore the regulatory function of microRNA-137 (miR-137) in oxidative stress-induced cardiomyocyte apoptosis. MATERIAL AND METHODS Cardiomyocytes were extracted from newborn C57BL/6 mice and cultured in vitro. Apoptosis was ind...

Beale. D.. Ketterer. B., Carne, T., Meyer, D. & Taylor, J . B. (1982) Eur. J. Biochem. 126. 459 463 Beale. D.. Meyer, D., Taylor, J. B. & Ketterer. B. (1983) Eur. J. Biochem. 137. 125 129 Ding. G. J.-F.. Lu. A. Y. H. & Pickett, C. B. (1985) J. B i d . Chem. 260. 13268 13271 Jakoby. W. B. & Habig. W. H. (1980) in Enzymutic Basis qf DeroxiCU/ i (Jn (Jakoby. W. B., ed.), vol. 2. pp. 63--94, Academ...

Traditional interactive system architectures such as MVC [Goldberg, A., 1984. Smaltalk-80: The Interactive Programming Environment, Addison-Wesley Publ.] and PAC [Coutaz, J., 1987. PAC, an implementation model for dialog design. In: Interact’87, Sttutgart, September 1987, pp. 431–436; Coutaz, J., 1990. Architecture models for interactive software: faillures and trends. In: Cockton, G. (Ed.), En...

Concentration factors (CF: Bq.kg-1 in wet algae/Bq.kg-1 in filtered seawater) for Cs-137 in Japanese coastal algae, were investigated during 1984-1990. Cs-137/Cs(stable) atom ratios were also examined to clarify the distribution equilibrium of Cs-137 in marine algae and sea water. The CFs in marine algae were within the range of 5.4 approximately 92, and the geometric mean of CF was 28 +/- 2 (s...

Of the natural processes that concentrate dispersed environmental contaminants, landscape fire stands out as having potential to rapidly concentrate contaminants and accelerate their redistribution. This study used rainfall simulation methods to quantify changes in concentration of a widely dispersed environmental contaminant (global fallout 137Cs) in soils and surface water runoff following a ...

Details of the research undertaken in our laboratory can be found at http://www.dstuns.iitm.ac.in/pradeep-research-group.php. A green route to synthesise glutathione protected atomically precise silver clusters by sunlight irradiation of silver thiolates confi ned in gel cavities, and the antibacterial properties of the as-synthesized clusters against gram-negative and gram-positive bacteria. A...

Long, balanced electron and hole diffusion lengths greater than 100 nanometers in the polycrystalline organolead trihalide compound CH3NH3PbI3 are critical for highly efficient perovskite solar cells. We found that the diffusion lengths in CH3NH3PbI3 single crystals grown by a solution-growth method can exceed 175 micrometers under 1 sun (100 mW cm(-2)) illumination and exceed 3 millimeters und...

A 45-year-old woman presented with generalised body itch, dark-coloured urine and pale stools for six day. Ultrasonography, endoscopic retrograde cholangiopancreatography and computed tomography revealed dilated intrahepatic ducts with stricture at the proximal common bile duct. The gallbladder was replaced by a large heterogeneous mass invading the liver and common bile duct. She underwent gal...