Intracranial subarachnoid hemorrhage (SAH) is a rare complication of myelography that can have serious consequences and presents a potentially life threatening complication in humans. In both humans and dogs [1-6], it may lead to raised intracranial pressure, the development of prolonged cerebral arterial spasm and cerebral ischemia [6-8]. The condition has been previously reported in two dogs ...

Cerebral microcirculation dysfunction might play an important role in symptomatic cerebral vasospasm (CVS), and this study was to investigate whether human tissue kallikrein (HTK) can alleviate it. In this study, forty-four rabbits were randomly divided into sham-operated, subarachnoid hemorrhage-operated (SAH), SAH+HTK groups and SAH+HTK+L-NNA groups (n = 11/group). Neurological function and f...

Cerebral vasospasm and ischemic damage are important causes of mortality and morbidity in patients affected by aneurysmal subarachnoid hemorrhage (SAH). Recently, i.p. administration of recombinant human erythropoietin (r-Hu-EPO) has been shown to exert a neuroprotective effect during experimental SAH. The present study was conducted to evaluate further the effect of r-Hu-EPO administration aft...

 Background and Aim: Secondary complications management of Subarachnoid Hemorrhage (SAH) is one of the therapeutic challenging issues during ICU[A1]  admission. The complications of patients with SAH admitted to the ICU of Imam Khomeini Hospital of Urumia were investigated in this study. Methods and Materials/Patients: In this descriptive study, the clinical complications of the patients with ...

Introduction Advances in brain imaging have dramatically changed our understanding of intracerebral hemorrhage (ICH). In the pre-CT era, many small ICHs were misclassified as ischemic strokes and patients with massive ICH or subarachnoid hemorrhage (SAH) were often difficult to correctly classify. This chapter reviews the epidemiology of non-traumatic ICH in light of modern neuroimaging and inc...

It has been known for over 80 years that brain injury may be associated with hypopituitarism, but recent evidence shows an even higher prevalence of anterior pituitary deficiencies than previously thought. A summary of the recent data on the prevalence of anterior pituitary deficiencies in sub-arachnoid hemmorage (SAH) and traumatic brain injury (TBI) survivors including the incidence of specif...

Subarachnoid hemorrhage (SAH) is associated with significant morbidity and mortality. We implemented an in-scanner rat model of mild SAH in which blood or vehicle was injected into the cistern magna, and applied multimodal MRI to study the brain prior to, immediately after (5min to 4h), and upto 7days after SAH. Vehicle injection did not change arterial lumen diameter, apparent diffusion coeffi...

OBJECTIVE Delayed cerebral ischemia (DCI) due to vasospasm is often undetected by clinical exam in patients with poor-grade subarachnoid hemorrhage (SAH). The purpose of this study was to identify quantitative EEG (qEEG) parameters that are most sensitive and specific for the detection of DCI in stuporous or comatose SAH patients. METHODS Of 78 consecutive Hunt-Hess grade 4 or 5 SAH patients ...