The present study investigates the antinociceptive properties of lupeol in models of inflammatory and post-operative pain, as well as its mechanisms of action. The effects of lupeol were tested against acetic acid-induced writhing, formalin test, carrageenan-induced hyperalgesia, and post-operative pain model. Cytokine levels were determined by ELISA. Mice motor performance was evaluated in the...

BACKGROUND A growing proportion of veterans treated at the Veterans Health Administration (VA) have a history of post-traumatic-stress-disorder (PTSD), and there exists a higher rate of PTSD amongst veterans than the general population. The purpose of this study is to determine the correlation between PTSD and intra-operative analgesia, intra-operative time, and anesthesia type for cataract sur...

Background: Excessive anxiety and stress can affect children’s physical and psychological health, hinder their ability to cope with surgery, encourage their negative behavior in association with health care, and may also inhibit their post-operative recovery. This study was conducted to determine the effects of pre-operative psychoeducational interventions on post-operative anxiety and pain in ...

BACKGROUND The high frequency of post-operative pain in the patients after laparoscopic cholecystectomy has led to the need to use multiple analgesic therapies. These include auriculotherapy, although not very good results have been obtained with the traditional techniques. OBJECTIVE To evaluate the effectiveness of modified auriculotherapy for post-operative pain control in laparoscopic chol...

introduction: tonsillectomy is one of the most common surgeries in the world and the most common problem is post-tonsillectomy pain and bleeding. the relief of postoperative pain helps increase early food intake and prevent secondary dehydration. one method for relieving pain is peritonsillar injection of epinephrine along with an anesthetic, which has been shown to produce variable results in ...

BACKGROUND The prevention and treatment of post-operative pain, and the promotion of comfort are the challenges facing practitioners working in the recovery room setting. Surgical pain produces autonomic, psychological, immunological and behavioural responses that can delay or inhibit normal healing. Nurses spend more time with patients experiencing pain than any other healthcare professional. ...

Eighteen patients, referred from an outside institution with massive, irreparable rotator cuff tears and loss of elevation, were treated with a latissimus dorsi tendon transfer as a salvage procedure for failed, prior, attempted rotator cuff repair. Clinical outcomes were measured by the American Shoulder and Elbow Surgeon's (ASES) score, pain level, and active range of motion. The average post...

this trial was performed to determine if a continuous low-dose infusion of methylprednisolone is as effective as its bolus of high-dose in reducing inflammatory response. the study was single-center, double-blinded randomized clinical trial and performed in a surgical intensive care unit of an academic hospital. in this study, 72 consecutive patients undergoing elective coronary artery bypass g...