The in vitro antimicrobial activity of the essential oil isolated from the aerial parts of Cymbopogon Olivieri (Boiss.) Bor, an aromatic grass of Iran was tested against three Gram-negative and four Gram-positive bacteria and also three fungi. The results of the bioassays showed that the oil has a remarkable antimicrobial activity. Bacillus subtilis and Candida albicans were more sensitive to t...

A. calamus that grows in province of Baluchistan and Kerman in Iran plays a major role in the revival of traditional medicine. Despite the useful role of this plant in many ailments, its anti-bacterial properties are not well understood. In this study, we investigated anti-bacterial activities of rhizomes ware of A. calamus against various strains of bacteria such as Staphylococcus aureus and E...

We previously synthesized several series of compounds, based on the 5-aryl-2-aminoimidazole scaffold, that showed activity preventing the formation of Salmonella enterica serovar Typhimurium and Pseudomonas aeruginosa biofilms. Here, we further studied the activity spectrum of a number of the most active N1- and 2N-substituted 5-aryl-2-aminoimidazoles against a broad panel of biofilms formed by...

Nowadays, uncontrolled and frequent use of antibiotics may cause emergence of microbial resistanceamong pathogenic agents. Therefore, the use of new synthetic and natural antimicrobial compounds isinevitable. One source of natural compounds in this respect comes from plants. The purpose of this study was to examine the antibacterial effects of peel extracts from sour and sweet pomegranate. Meth...

background/objective: neonatal septicemia is one of the major causes of mortality in newborns. the aim of this study is to evaluate the clinical manifestations and laboratory findings in positive blood culture in neonatal septicemia. methods: in this retrospective study, we allocated 100 records positive blood culture of neonates suffering from septicemia. a questionnaire was completed for each...

In this study we evaluated the antibacterial activity of the crude hydroalcoholic extracts, fractions, and compounds of two plant species, namely Rosmarinus officinalis and Petroselinum crispum, against the bacteria that cause urinary tract infection. The microdilution method was used for determination of the minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC). T...

Spenolimycin is a new spectinomycin-type antibiotic isolated from Streptomyces gilvospiralis sp. nov. In vitro, it was active against a wide variety of aerobic Gram-positive and Gram-negative bacteria and Neisseria gonorrhoeae. It was two to four-fold more active against N. gonorrhoeae than spectinomycin. Spenolimycin was effective in the standard mouse protection test against Escherichia coli,...

BACKGROUND Bacterial vaginosis is a global concern due to the increased risk of acquisition of sexually transmitted infections. OBJECTIVES To determine the prevalence of bacterial vaginosis and bacteria causing aerobic vaginitis. METHODS A cross-sectional study was conducted among 210 patients between September 2015 and July 2016 at St. Paul's Hospital. Gram-stained vaginal swabs were exami...

conclusions optimization of medium composition and synergistic antimicrobial activity on the cyanobacteria could lead to production of effective antimicrobials. results c. leptolyngbya had antimicrobial activity individually and in synergy with antibiotics against gram-positive and gram-negative bacteria. the highest activity of the chloroform extract was on gram positive strains and its effect...

in many parts of the world there is a rich tradition in the use of herbal medicine for the treatment of many infectious diseases. because of the side effects and the resistance that pathogenic microorganisms build against the antibiotics, much recent attention has been paid to extract the biologically active compounds from plant species used in herbal medicine. in this study different parts of ...