Background: A successful endodontic treatment is inseparable from the right choice of root canal dressing. The medicaments would result in patient satisfaction. Enterococcus faecalis (E. faecalis) and Porphyromonas gingivalis (P. gingivalis) are usually found failed treatments. Calcium hydroxide a gold standard dressing that creates an alkaline environment has bactericidal effect. Commercially,...

Porphyromonas gingivalis merupakan bakteri patogen dalam penyakit periodontitis kronis. Kandungan senyawa organik daun sirih merah (Piper crocatum) memiliki efek antibakteri. Ekstrak Piper crocatum diharapkan dapat digunakan sebagai terapi penunjang Penelitian ini bertujuan untuk mengetahui antibakteri ekstrak melalui uji daya hambat terhadap gingivalis. Prosedur kerja dengan membuat sampel eta...

The introduction of multilocus sequence typing (MLST) in infectious disease research has allowed standardized typing of bacterial clones. Through multiple markers around the genome, it is possible to determine the sequence type (ST) of bacterial isolates to establish the population structure of a species. For the periodontal pathogen, Porphyromonas gingivalis, the MLST scheme has been establish...

Purpose: To detect the effect of Resolvin D1 (RvD1) on Developmental endothelial locus-1 (Del-1) and cytokine expressions human gingival fibroblast cells exposed to Porphyromonas gingivalis lipopolysaccharide (P. gingivalis-LPS).
 
 Material Methods: The RvD1 cell viability fibroblasts P. gingivalis-LPS were determined by MTT (3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromi...

The anaerobic Gram-negative bacterium Porphyromonas gingivalis is considered the keystone of periodontitis diseases, a set inflammatory conditions that affects tissues surrounding teeth. In recent years, major virulence factors exploited by P. have been identified and characterized, including cocktail toxins, mainly proteases called gingipains, which promote gingival tissue invasion. These effe...

A gingival crevice model (epithelial cell-Porphyromonas gingivalis-neutrophil) was established and used to profile gingipain, matrix metalloproteinase (MMP), MMP mediators [neutrophil gelatinase-associated lipocalin (NGAL) and tissue inhibitor of metalloproteinases 1 (TIMP-1)] and cytokine networks. Smoking is the primary environmental risk factor for periodontitis. Therefore, the influence of ...