نتایج جستجو برای: polymerization kinetics
تعداد نتایج: 125927 فیلتر نتایج به سال:
Crawling motion is ubiquitous in eukaryotic cells and contributes to important processes such as immune response and tumor growth. To crawl, a cell must adhere to the substrate, while protruding at the front and retracting at the rear. In most crawling cells protrusion is driven by highly regulated polymerization of the actin cytoskeleton, and much of the biochemical network for this process is...
Chemotaxis requires localized F-actin polymerization at the site of the plasma membrane closest to the chemoattractant source, a process controlled by Rac/Cdc42 GTPases. We identify Dictyostelium RacB as an essential mediator of this process. RacB is activated upon chemoattractant stimulation, exhibiting biphasic kinetics paralleling F-actin polymerization. racB null cells have strong chemotaxi...
Actin is a key component of the cytoskeleton, which plays central roles in cell motility, division, growth, and tensile strength. To enable this wide range of transient mechanical processes and properties, networks of actin filaments continuously disassemble and reassemble via active de/re-polymerization. However, the question remains as to how de/re-polymerization kinetics of individual actin ...
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