Estrogen acts in the brain to regulate female reproductive physiology and behavior, and protein kinase C (PKC) is estrogen-regulated in many estrogen-responsive tissues. We examined whether estrogen regulates PKC in the hypothalamus (HYP) and preoptic area (POA), brain regions which mediate estrogenic control of female reproductive function. PKC activity in tissue from hormone-treated and contr...

Sex and seasonal differences in the brain occur in many species and are often related to behavioral expression. For example, morphology of limbic regions involved in male sex behavior are larger in males than in females, and sometimes are larger in the breeding than non-breeding season. Morphology can often be altered in adulthood by manipulating levels of steroid hormones. In untreated green a...

We have conducted joint research studies on the management of brown ring patch since 2010. From a feld research perspective, this disease has been challenging to work with because it is diffcult to fnd naturally infected putting greens with uniform disease incidence and severity. The main body of research presented in this paper comes from work conducted in 2010 and 2011 on a putting green in N...

Large-scale daily commuting data were combined with detailed geographical information system (GIS) data to analyze the loss of transport efficiency caused by drivers' uncoordinated routing in urban road networks. We used Price of Anarchy (POA) to quantify the loss of transport efficiency and found that both volume and distribution of human mobility demand determine the POA. In order to reduce P...

Gonadotropin-inhibitory hormone (GnIH) is a hypothalamic neuropeptide that inhibits gonadotropin secretion and socio-sexual behaviours. Oestrogen (neuroestrogen) synthesized in the brain from androgen by aromatase regulates male socio-sexual behaviours. Here we show that GnIH directly activates aromatase and increases neuroestrogen synthesis in the preoptic area (POA) and inhibits socio-sexual ...

ZEN is a CORBA ORB designed to support distributed, realtime, and embedded (DRE) applications that have stringent memory constraints. This paper discusses the design and performance of ZENs portable object adapter (POA) which is an important component in a CORBA object request broker (ORB). This paper makes the following three contributions to the study of middleware for memory-constrained DRE ...

Bitcoin and its underlying blockchain mechanism have been attracting much attention. One of their core innovations, Proof-of-Work (PoW), is notoriously inefficient which potentially motivates a centralization of computing power, defeating the original goal of decentralization. Proof-of-Stake (PoS) is later proposed to replace PoW. However, both PoW and PoS have different inherent advantages and...

the present study was conducted in the rangeland of glandrood watershed in the province of mazandaran. the objective of this study was to compare between the ecological amplitude of festuca ovina l., and poa bulbosa l., using the function hof along the gradient of the environmental variables. for this purpose 150 plots of 1m2 were established along the altitude gradient. the sampling method was...

Pyrazinamide (PZA), an analog of nicotinamide, is a prodrug that requires conversion to the bactericidal compound pyrazinoic acid (POA) by the bacterial pyrazinamidase (PZase) activity of nicotinamidase to show activity against Mycobacterium tuberculosis. Mutations leading to a loss of PZase activity cause PZA resistance in M. tuberculosis. M. kansasii is naturally resistant to PZA and has redu...