Dichloroacetate (DCA) is a simple and small anticancer drug that arouses the activity of the enzyme pyruvate dehydrogenase (PDH) through inhibition of the enzyme pyruvate dehydrogenase kinases (PDK1-4). DCA can selectively promote mitochondria-regulated apoptosis, depolarizing the hyperpolarized inner mitochondrial membrane potential to normal levels, inhibit tumor growth and reduce proliferati...

Planar laser-induced fluorescence (PLIF) of nitric oxide is used to measure a component of the velocity field for the Mach 7 flow around a cone. Velocities are measured in the freestream, shock layer, and the separated region behind the cone. The measurements are compared with computational fluid dynamics (CFD) codes. The comparison indicates that the CFD correctly predicts the flow over the fo...

In situ planar laser-induced fluorescence (PLIF) shows the effects of pyrolysis peak temperature and holding time on formation 3–5 rings polyaromatic hydrocarbons (PAHs) in vapour phase during biomass samples.

Dichloroacetate (DCA) is a simple and small anticancer drug that arouses the activity of the enzyme pyruvate dehydrogenase (PDH) through inhibition of the enzyme pyruvate dehydrogenase kinases (PDK1-4). DCA can selectively promote mitochondria-regulated apoptosis, depolarizing the hyperpolarized inner mitochondrial membrane potential to normal levels, inhibit tumor growth and reduce proliferati...

Dichloroacetate (DCA) is a simple and small anticancer drug that arouses the activity of the enzyme pyruvate dehydrogenase (PDH) through inhibition of the enzyme pyruvate dehydrogenase kinases (PDK1-4). DCA can selectively promote mitochondria-regulated apoptosis, depolarizing the hyperpolarized inner mitochondrial membrane potential to normal levels, inhibit tumor growth and reduce proliferati...

By use of high-speed planar laser-induced fluorescence (PLIF) imaging, the evolution of turbulent reactive flows was recorded and studied in real time in a filmlike manner. The technique was used to track the concentration field of the OH radical, which was produced during spark ignition of a turbulent methane/air mixture. The results were compared qualitatively to a two-dimensional direct nume...