INTRODUCTION Intra-articular injections of platelet rich plasma (PRP) for the treatment of knee osteoarthritis have been shown to reduce pain and improve joint function. The aim of this study is to examine the joint function by adding intra-articular growth hormone to platelet rich plasma. This study was performed on the individuals with knee osteoarthritis and under ultrasound guidance. METH...

BACKGROUND Considerable evidence implicates CD40 signaling in the pathogenesis of atheromas. Exposure to CD40 ligand induces platelet-leukocyte conjugation, a heightened expression of inflammatory cytokines, matrix-degrading enzymes, and procoagulant factors. OBJECTIVES To investigate the association between plasma soluble CD40 ligand (sCD40L) and platelet-monocyte aggregates in patients with...

We reported previously that dietary intake of alpha-linolenic acid (ALA) reduces atherogenesis and inhibits arterial thrombosis. Here, we analyze the substantial increase in the platelet count induced by ALA and the mechanisms of reduced platelet clearance. 8-week-old male apolipoprotein E knockout (ApoE) mice were fed a 0.21g% cholesterol diet complemented by either a high (7.3g%) or low ALA (...

Plasma ionized calcium, platelet cytosolic calcium (using the fura-2 method in gel-filtered platelets), parathyroid hormone (both the intact hormone and a midmolecule portion), calcitriol, and calcidiol were measured in 19 untreated male patients with essential hypertension and 19 age-matched normotensive male research subjects. Mean levels of platelet cytosolic calcium, parathyroid hormone, ca...

Background Platelets have an important contribution in pathogenesis of different infectious and inflammatory disorders. This study was performed to identify the diagnostic value of platelet count (PLT), and platelet indices in children with acute pyelonephritis (APN).  Materials and Methods In a cross sectional case control s...

conclusions tissue engineering may open a new window in cleft palate reconstruction. stem cells and growth factors play key roles in this field. results we reported a summary of the key-points concerning cleft palate development, the genes involving this defect, current therapeutic strategies, recently novel aspects, and future advances in treatments for easy and fast understanding of the conce...

Platelet adherence surrounding leucocytes in a rosette formation or platelet satellitism is a rare phenomenon. This finding has been observed almost exclusively in Ethylenediaminetetraacetic acid treated blood at room temperature. The mechanism underlying this phenomenon is not fully understood. In many reports of platelet satellitism platelets clump to polymorphonuclear neutrophils in healthy...

OBJECTIVE To determine whether the ratio of first-trimester aspartate aminotransferase (AST) to platelet index (APRI) score will be useful as a new determinant hemolysis, elevated liver enzymes, low platelets (HELLP) syndrome that may develop in later stages pregnancy Study Design: Descriptive-analytical study. PLACE AND DURATION OF STUDY Perinatology Clinic Etlik Zubeyde Hanim Maternity and Wo...

Introduction: The amount of platelet count in platelet-rich plasma (PRP) is very important for the concentration growth factors, which play a major role effectiveness PRP.
 Aim: aim this study was to investigate effects demographic and clinical parameters on number platelets Materials And Methods: data 50 patients who received PRP our stem cell center were scanned retrospectively electroni...