OBJECTIVE The estimation of platelet count from blood smears is a daily routine laboratory test, which should be systematic each time the automated count is erroneous. In our laboratory, we estimate the platelet count indirectly by using the automated red blood cell (RBC) and calculating the platelet count on the basis of the red cell: platelet ratio in a stained blood film. In this study, we a...

Blood transfusion centers are under considerable pressure to produce platelet concentrates with a shelf life limit of 3 to 5 days. Many approaches have been investigated experimentally to produce new hemostatically active platelet products that are capable of long term storage. In this article infusible platelet membrane will be explained as a platelet substitute versus conventional liquid-stor...

PURPOSE We correlated platelet count to renal tumor characteristics, and evaluated the potential prognostic value of thrombocytosis in localized and metastatic tumors. MATERIALS AND METHODS A total of 804 patients operated on for a renal tumor in 2 French centers were included in this study. In all cases TNM stage, Fuhrman grade, tumor size, nodal invasion, ECOG score, histological subtype an...

Introduction: Diabetes mellitus is a global pandemic and a complex disease characterized by chronic hyperglycaemia, metabolic abnormalities, long term macro – microvascular abnormalities involving the blood vessels, eyes, kidneys and nerves. Platelet parameters such as high platelet count and mainly high mean platelet volume (MPV) have been reported in diabetic patients, contributing to the inc...

Thrombocytopenia is a well-known complication of liver cirrhosis. Although the pathogenesis of thrombocytopenia is not well understood, splenic congestion resulting from portal hypertension is considered the most significant underlying mechanism. Therapeutic measures that lower portal hypertension, such as transjugular intrahepatic portosystemic shunt (TIPS), are expected to improve thrombocyto...

bopag increases platelet numbers in thrombocytope-nic patients with HCV infection and cirrhosis, allowing for effective antiviral therapy. Gastroenterology 2014; 146: 442-52. Thrombocytopenia is defined as platelet count being <150.000 cells/μL. A platelet count of 50.000 to 75.000/μL means moderate thrombocytopenia and a platelet count below 50.000 indicates severe throm-bocytopenia. It is com...