Introduction: Trophic ulcers are the major cause of disability in leprosy patients. The disease imposes a social stigma and economic burden these patients which interferes with regular treatment resulting defaulters. Chronicity ulcer complications like osteomyelitis malignancy became an ever challenging task for treating physician. Newer modalities on search decreasing duration preventing recur...

Marfan syndrome classically presents with aortic root aneurysms. Aortic ectasia causes diverse blood flow alterations, influencing the behavior of coagulation factors and platelet activity. Heparin resistance has also been reported associated Syndrome in a small number patients, probably due to antithrombin III (ATIII) deficiency or various mutations. The ascending aorta valve are replaced pros...

Abstract
 Bacground: Blood product management and need during the Covid 19 pandemic is a controversial issue. The effect of reduced blood donation due to on has not yet been determined.
 Objectives: aim this study determine rate transfusion in COVID-19 patients.
 Material Method: 9-month period between 01.07.2019-31.03.2020 before 01.04.2020-31.12.2021 were determined as time for...

INTRODUCTION For many years, platelet concentrates have been used for the prevention as well as treatment of bleeding disorders, especially in those patients with haematological problems involving platelet disorders as well as refractoriness, In addition, platelet concentrates (PCs) have been widely used to support patients undergoing bone marrow transplantation or who are receiving myelotoxic ...

BACKGROUND Thrombocytopenia is a frequent finding in critically ill cancer patients for whom indications of platelet transfusions are unclear. We herein addressed the current practices in platelet transfusion and the risk of bleeding in cancer patients with hypoproliferative thrombocytopenia in the intensive care unit (ICU). METHODS A retrospective monocenter study over a 7-year period was co...

BACKGROUND Previous studies of bioactive molecules in platelet-rich plasma (PRP) have documented growth factor concentrations that promote tissue healing. However, the effects of leukocytes and inflammatory molecules in PRP have not been defined. HYPOTHESIS The hypothesis for this study was that the concentration of growth factors and catabolic cytokines would be dependent on the cellular com...

Fetal/neonatal alloimmune thrombocytopenia (F/NAIT) is the most frequent cause of haemorrhagic morbidity and mortality in otherwise healthy term infants and occurs in 1 in 1000 to 1 in 2000 pregnancies [1]. Maternal HPA-1a alloimmunization is responsible for the majority of NAIT [1], and only a few cases of NAIT caused by anti-HPA-3a have been published [2–4]. However, based on gene frequencies...

Platelet rich plasma (PRP) has been shown to clinically accelerate healing of both soft and hard tissues. As a result, it has gained increasing popularity. However, the clinical effectiveness of each type of PRP preparation method can vary in technique and efficiency, and current methods to evaluate the platelet concentration efficiency of PRP systems have several limitations. Therefore, the pu...