The classical attitude of Nuclear Medicine practitioners on matters of peptide-receptor interactions has maintained an intrinsic monogamic character since many years. New advances in the field of biochemistry and even in clinical Nuclear Medicine have challenged this type of thinking, which prompted me to work on this review. The central issue of this paper will be the use of somatostatin analo...

Obesity is a major risk factor in the development of cardiovascular disease, type 2 diabetes, and its pathophysiological precondition insulin resistance. Very little is known about the metabolic changes that occur in the myocardium and consequent changes in cardiac function that are associated with high-fat accumulation. Therefore, cardiac function and metabolism were evaluated in control rats ...

We present a framework for the modelling of cell motility in heterogeneous environments. The cell membrane is represented by an evolving surface, with the movement of the cell determined by the interaction of forces that act normal to the surface. The biochemistry is modelled through partial differential equations posed on the cell membrane. For the mechanics, we propose a force balance on the ...

Technological advancements in the fields of analytical chemistry and biochemistry have allowed for characterization of a broad range of chemical exposures that may be collectively involved with the onset of chronic illnesses. New developments in mass spectrometry (MS) have yielded measurements of thousands of chemicals in a single human specimen [1]. The comprehensive measurement and characteri...

background: there are varieties of purification techniques for separation of human plasma proteins such as salting out, ion exchange chromatography, and ethanol fractionation. there are limitations for each method, for example in salting out method, the salt has to be removed in an additional step. ion exchange chromatography is difficult for scaling up, and plasma fractionation is a time consu...

BACKGROUND Ficus thonningii is commonly used in traditional medicine across the African continent. We investigated the effects of crude Ficus thonningii extracts on growth, morphology and morphometry of the abdominal viscera and clinical biochemistry of neonatal rats. MATERIALS AND METHODS Forty, 6-day old Sprague Dawley rat pups were orally gavaged once daily with either low (50 mg.kg(-1) b....

In the first and second of these works, Galen thoroughly refutes the statements of his predecessor, Erasistratus, point by point, and firmly establishes his own views on the importance of venesection. We are reminded here of the uncompromising thoroughness of Sir William Harvey in De Moto Cordis (1628). Galen, however, lacks Harvey's characteristic ability to incorporate simple yet decisive exp...

The elucidation of the detailed chemical mechanisms involved in biological, and particularly in enzymatic, processes has received considerable attention in recent years. Increasingly, the theories and methods of physical organic chemistry are being applied to this problem. Kosower has attempted to review the advances made in this field, as well as to suggest areas of biochemistry which should p...