PURPOSE To assess the anti-plaque and anti-gingivitis effects of a dentifrice containing 0.3% triclosan, 2% copolymer and 0.243% (1,100 ppm) sodium fluoride in subjects with moderate plaque-induced gingivitis. METHODS This was a single center, monadic study. Subjects had at least 20 teeth remaining in the functional dentition, excluding third molars. Following a baseline examination for plaqu...

Coronary artery disease (CAD) is characterised by progressive atherosclerotic plaque leading to flow-limiting stenosis, while myocardial infarction (MI) occurs due to plaque rupture or erosion with abrupt coronary artery occlusion. Multiple inflammatory pathways influence plaque stability, but direct assessment of endothelial inflammation at the site of coronary artery stenosis has largely been...

OBJECTIVE Protective properties of high-density lipoproteins (HDL) may include reverse cholesterol transport and suppression of oxidation and inflammation. These were investigated in vivo, as were the effects of HDL on the characteristics of atherosclerotic lesions. METHODS AND RESULTS Male apolipoprotein E knockout (apoE-/-) and apoE-/- mice expressing human apolipoprotein AI (hAI/apoE-/-) w...

Atherosclerotic plaque calcification is a frequent and severe complication of atherosclerosis with significant clinical consequences. The causes of vascular calcification are multifactorial and include impaired phosphate metabolism, increased inflammation with consequent oxidative stress, alterations in systemic metabolic factors (hyperglycemia and hyperlipidemia), and alterations in tissue mec...

The fundamental role of inflammation in atherosclerosis is well established through animal and autopsy studies, which has promoted the development of imaging approaches for in vivo assessment of plaque inflammation. Among many biological targets implicated in plaque inflammation, macrophages and neovessels have gained broad interest because they are abundant and detectable by clinical imaging m...

AIM The aim of the study was to asses the effect of the use of interdental brushes (IDB) in patients as an adjunct to toothbrushing compared with toothbrushing alone or other interdental oral hygiene devices on plaque and the clinical parameters of periodontal inflammation. MATERIAL AND METHODS MEDLINE-PubMed and the Cochrane Central register of controlled trials (CENTRAL) were searched throu...

Introduction: Glass ionomer and polycarboxylate cement have different effects on the marginal seal, microleakage, pulp tissue stimulation, and gingival health. The purpose of this study was to assess the effect of these cement on the gingival health of primary molars restored with stainless steel crowns (SSC). Methods: A total number of 34 children were selecte...

AIMS Rupture-prone atherosclerotic plaques are characterized by inflammation and a large necrotic core. Inflammation is linked to high metabolic activity. Advanced glycation endproducts (AGEs) and their major precursor methylglyoxal are formed during high metabolic activity and can have detrimental effects on cellular function and may induce cell death. Therefore, we investigated whether plaque...

Background and Purpose—Carotid endarterectomy is currently guided by angiographic appearance on the assumption that the most stenotic lesion visible at angiography is likely to be the lesion from which future embolic events will arise. However, risk of plaque rupture, the most common cause of atherosclerosis-related thromboembolism, is dictated by the composition of the plaque, in particular th...

conclusions similar to previous studies, this study could not show the superiority of electric toothbrush over manual in plaque removal. after 72 hours, the mean of plaque index was greater in buccal than in lingual surface, which may be attributed to the natural cleansing action of the tongue. results the mean of plaque index was 2.13 ± 0.83 and 2.11 ± 1.01 in the manual and electric toothbrus...