Background: Sacral pit is a shallow or deep dimple in the lower sacral region, with a reported prevalence of 3-5% among newborns. The aim of the present study was to investigate spinal cord abnormalities in newborns with sacral pit via ultrasound examinations. Methods: In this descriptive study, 3071 infants born at 34-42 weeks of gestation were studied in hospitals affiliated to Islamic Azad U...

The determination of the Ultimate Pit Limit (UPL) is the first step in the open pit mine planning process. In this stage that parts of the mineral deposit that are economic to mine are determined. There are several mathematical, heuristic and meta-heuristic algorithms to determine UPL. The optimization criterion in these algorithms is maximization of the total profit whilst satisfying...

OBJECTIVES To elucidate the visual significance of the foveal pit by measuring foveal architecture and function and to reassess use of the term foveal hypoplasia (as visual acuity can vary among patients who lack a pit). METHODS We describe 4 patients who lack a foveal pit. Visual acuities ranged from 20/20 to 20/50. Stratus and Cirrus (Carl Zeiss Meditec, Dublin, California) optical coherenc...

Overexpression of the proinflammatory cytokine macrophage migration inhibitory factor (MIF) is linked to a number of autoimmune diseases and cancer. MIF production has been correlated to the number of CATT repeats in a microsatellite region upstream of the MIF gene. We have characterized the interaction of pituitary-specific positive transcription factor 1 (Pit-1) with a portion of the MIF prom...

Plant water transport occurs through interconnected xylem conduits that are separated by partially digested regions in the cell wall known as pit membranes. These structures have a dual function. Their porous construction facilitates water movement between conduits while limiting the spread of air that may enter the conduits and render them dysfunctional during a drought. Pit membranes have bee...

We characterized pit and mound (PM) topography resulting from catastrophic wind in the Coweeta Basin, and located 48 PMs a across a variety of forest types. Our measurements included pit length, width, and depth; and mound height, thickness, and width. Species of fallen trees were identified, and DBH (diameter at breast height, 1.37 m) was measured for biomass determination. We identified five ...

Aquatic field studies were conducted in Tha Mai District, Chanthaburi Province, Thailand. Larval habitats of Anopheles dirus were examined from November 1986 through June 1988 in 42 manmade gem pits. Larvae were found in pits containing clear water under full or partial shade. The abundance of different kinds of mosquito larvae were related to seasonal changes in these aquatic habitats. Variati...

To test the role of wtPIT-1 (PITWT) or PIT-1 (R271W) (PIT271) in somatolactotroph cells, we established, using inducible lentiviral vectors, sublines of GH4C1 somatotroph cells that allow the blockade of the expression of endogenous PIT-1 and/or the expression of PITWT or PIT271, a dominant negative mutant of PIT-1 responsible for Combined Pituitary Hormone Deficiency in patients. Blocking expr...