Piperine is a natural cytotoxic agent aware of various therapeutic acts. The aim this study to look into the effects solvent polarity on solvent-free energy, dipole moment, polarizability, and hyper-polarizability first order, as well molecular properties including chemical hardness softness, potential, electronegativity, electrophilicity index, in order gain better understanding its reactivity...

Black pepper ( Piper nigrum L.) is a popular spice that grown as tropical and subtropical plant throughout the world. The leaf, flower, fruit, root are most important elements of plant. Asexual or vegetative propagation becoming highly popular, although sexual approach still used for vine cultivation. For mass production plant, in vitro culture also used. bioactive components contained them ext...

Abstract: Multidrug resistance (MDR) bacterial infection is the next pandemic waiting behind COVID-19 with annual mortality rate 700000 worldwide. Among MDR bacteria, Escherichia coli, Staphylococcus aureus, Klebsiella pneumoniae, Acinetobacter baumannii, Pseudomonas aeruginosa, Enterococcus faecium and faecalis are showing average of 50 to 80% ampicillin, amoxicillin, third-generation cephalos...