The hypothetical incidence of reproductive cancers resulting from oral contraceptive use was estimated in several models comparing the cumulative lifetime incidence of cancer of the breast, cervix, ovary and endometrium expected in pill users with the incidence expected in nonusers. The potential number of cancer-free days that would be gained or lost by pill users was compared with similar est...

A step-wise approach to identify valid and feasible methods to detect non-adherence to tuberculosis drugs was evaluated in a prospective study among pulmonary tuberculosis patients in an outpatient clinic in Indonesia. First, adherence was measured by self-reporting with the standardized Morisky questionnaire, physician assessment, pill-count, visit attendance, diary and an electronic medicatio...

The present study aimed to investigate the effect and underlying mechanisms of the Ruyi Zhenbao pill on neurological function following cerebral ischemia/reperfusion in rats. Male Sprague-Dawley rats underwent middle cerebral artery occlusion following reperfusion. The rats received intragastrically either sodium carboxymethyl cellulose (control and model groups) or Ruyi Zhenbao pill at doses o...

The article by Potts et al, “The Pill is Mightier than the Sword,” points out that family planning has an important role to play in building peace by increasing women’s empowerment and their agency, ultimately helping peacebuilding efforts. Evidence has demonstrated that family planning programs are cost effective, produce quick results, help women and couples meet their desired fertility level...

The study aimed to develop and validate an instrument capable of measuring non-adherence to drug treatment in its multiple dimensions. The Questionário de Adesão a Medicamentos (Adherence to Medicines Questionnaire) with three questions was applied to 46 people with arterial hypertension in the city of Blumenau, Southern Brazil, in 2006. Non-adherence measures obtained were compared to four oth...

OBJECTIVE To identify family-reported, adherence-related barriers for adolescents with inflammatory bowel disease (IBD) and examine their relationship to 6-MP/azathioprine and 5-ASA medication adherence. METHODS Participants included 74 adolescents, aged 13-17 years, diagnosed with IBD and their caregivers. Adolescents and caregivers jointly completed a measure of barriers to medication adher...

To examine how measuring adherence at 3 weeks by self-report and pill counts compares to measurements 7 in a pre-randomization run-in period. Study within trial of an international parallel group randomized controlled (RCT) that spironolactone placebo. Adults receiving dialysis enter 8-week active period with spironolactone. Adherence was assessed both subgroup participants weeks. 332 entered t...

INTRODUCTION With an ageing population, end-of-life care is increasing in importance. The present work investigated characteristics and time trends of older peoples' attitudes towards euthanasia and an end-of-life pill. METHODS Three samples aged 64 years or older from the Longitudinal Ageing Study Amsterdam (N=1284 (2001), N=1303 (2005) and N=1245 (2008)) were studied. Respondents were asked...