See related article, pages 1638–1643. In the past decade there has been considerable scientific discussion about the metabolic state of the tissue surrounding a brain hemorrhage. The scientific discussion has focused mostly on the question of whether brain ischemia is present in this “penumbral tissue,” which has great clinical relevance because the presence of ischemia would drive clinical tre...

PURPOSE To determine the cause of negative dysphotopsia and the location, appearance, and relative intensity of such images in pseudophakic eyes. SETTING Baylor College of Medicine, Houston, Texas, USA. DESIGN Reporting available data addressing a specific clinical question. METHODS Negative dysphotopsia was simulated using the Zemax optical design program. The nominal values for the pseu...

There has been a disturbing rise in harmful speech during COVID-19. Many have shocked by the deluge of malign information, which disseminated widely and rapidly on account technological advancement, globalization, digital interconnectivity. But we should not surprised. The historical record reveals that pandemics inevitably lead to an increase false information hate speech. This paper makes two...

The development of clinical stroke therapies remains elusive. The neuroprotective efficacies of thousands of molecules and compounds have not yet been determined; however, screening large volumes of potential targets in vivo is severely rate limiting. High throughput screens (HTS) may be used to discover promising candidates, but this approach has been hindered by the lack of a simple in vitro ...

BACKGROUND AND PURPOSE It has been suggested that CT Perfusion acquisition times <60 seconds are too short to capture the complete in and out-wash of contrast in the tissue, resulting in incomplete time attenuation curves. Yet, these short acquisitions times are not uncommon in clinical practice. The purpose of this study was to investigate the occurrence of time attenuation curve truncation in...