We demonstrate photothermal optical coherence tomography (OCT) imaging in highly scattering human breast tissue ex vivo. A 120 kHz axial scan rate, swept-source phase-sensitive OCT system at 1300 nm was used to detect phase changes induced by 830 nm photothermal excitation of gold nanoshells. Localized phase modulation was observed 300-600 microm deep in scattering tissue using an excitation po...

We performed a visualization of membrane proteins labeled with 10-nm gold nanoparticles in cells, using an all-optical method based on photothermal interference contrast. The high sensitivity of the method and the stability of the signals allows 3D imaging of individual nanoparticles without the drawbacks of photobleaching and blinking inherent to fluorescent markers. A simple analytical model ...

We demonstrate that the quantum-mechanical description of Rutherford scattering has a photonic counterpart in a new form of single particle photothermal microscopy. Using a split detector we provide experimental evidence that photons are deflected by a photothermal potential that is created by a local refractive index change around a heated nanoparticle. The deflection experienced is shown to b...

W18O49 with a tunable oxidation state was prepared by addition of NaNO3 or NaBH4 as a redox agent in the solvothermal system. The addition of redox agents has no influence on the crystallization of W18O49. The obtained W18O49 structures keep their morphology as a bundle of nanowires with a regular hexagonal on the cross-section. W18O49 exhibits strong valence-dependent absorption features in th...

Background: Nowadays, it is needed to explore new routes to treat infectious bacterial pathogens due to prevalence of antibiotic-resistant bacteria. Antimicrobial photothermal therapy (PTT), as a new strategy, eradicates pathogenic bacteria.Objective: In this study, the antimicrobial effects of a carbon nanoparticles-polypyrrole nanocomposite (C-PPy) upon laser irradiation were investigat...

Introduction: Recently, nanographene oxide (NGO) is proven to be as a great candidate for drug delivery, and phototherapies cancer. Photothermal sensitivity of NGO and its optical absorption in the NIR region lead to photothermal ablation of tumors. Nevertheless, the major drawback of GO is its toxicity in biological systems, To overcome this problem, nanoscale GO prepare with...

Photothermal-Gas Synergistic Cancer Therapy In article number 2206749, Benhui Hu, Yun Liu, and co-workers propose a cascade reaction-promoted CO release strategy to realize augmented photothermal-gas synergistic cancer therapy. Gold-based porphyrinic coordination polymer nanosheets synthesized by simple aqueous phase reaction, with ultrasmall zero-valent gold as the node, have advantages of hig...

A novel highly biocompatible nanosystem containing Mg nanoparticles is reported, characterized and tested as a suitable and non-toxic tool for photothermal therapy.

Gelatin-stabilized copper sulphide nanoparticles with conjugated doxorubicin have been developed for combined photoacoustic imaging, enzyme-responsive drug release and photothermal therapy.

The remarkable photothermal properties of pegylated nickel-bis(dithiolene) complexes in water can induce cell death under laser irradiation in the near infrared (NIR) region.