Cross-reactive T cell responses induced by a primary dengue virus infection may contribute to increased disease severity following heterologous infections with a different virus serotype in a phenomenon known as the original antigenic sin. In this study, we developed and analyzed in-host models of T cell responses to primary and secondary dengue virus infections that considered the effect of T ...

Human sera from Lodwar (77 sera), Nzoia (841 sera), Masinga (251 sera), Laisamis (174 sera) and the Malindi/Kilifi area (556 sera) in Kenya were tested by indirect immunofluorescence for antibodies against Marburg, Ebola (Zaire and Sudan strains), Congo haemorrhagic fever, Rift Valley fever and Lassa viruses. Antibodies against Ebola virus, particularly the Zaire strain, were detected in all re...

The virus was first isolated in April 1947 from a rhesus macaque monkey placed cage the Ziika Forest of Uganda, near Lake Victoria, by scientists Yellow Fever Research Institute. A second isolation mosquito A. africanus followed at same site January 1948. When developed fever, researchers its serum

BACKGROUND & OBJECTIVES Since not much information on Chandipura virus is available, an attempt was made to study the growth kinetics of the virus in certain vertebrate, invertebrate cell lines and embryonated chicken eggs. METHODS Comparative study of Chandipura virus (CHPV) growth kinetics in three vertebrate cell lines [Vero E6, Rhabdo myosarcoma (RD), Porcine stable kidney (PS) cell lines...

The Bunyaviridae represents the largest family of segmented RNA viruses, which infect a staggering diversity of plants, animals, and insects. Within the family Bunyaviridae, the Phlebovirus genus includes several important human and animal pathogens, including Rift Valley fever virus (RVFV), severe fever with thrombocytopenia syndrome virus (SFTSV), Uukuniemi virus (UUKV), and the sandfly fever...

BACKGROUND Bwamba virus (Genus Bunyavirus, family Bunyaviridae) is widely distributed in Africa. It causes many unidentified fevers because of its benign nature. OBJECTIVES Samples of blood from patients were received at Uganda Virus Research Institute for diagnosis and confirmation of infections. Mosquito collections obtained in the O'nyong-nyong virus fever epidemic in Rakai in 1997 were al...

Sango Virus (SANV) is a member of the Simbu serogroup within order Bunyavirales, family Peribunyaviridae, genus Orthobunyavirus. In end October, 2019, two SANV virus were identified and isolated from sera sampled symptomatic cows, which manifested fever, milk reduction diarrhea.

Ebola virus disease is the important emerging disease in Africa. This infection is deadly and has the main clinical feature as an acute hemorrhagic fever. The main hematological alteration in this infection is the platelet change. However, the change in other hematological parameters should be mentioned. 

Covid-19 is a novel virus with high affinity to spread in the community. In December 2019, it was first identified in Wuhan, China. The symptoms are non-specific, so fever, cough, dyspnea, are prominent features. Respiratory failure and mortality have also been reported. The most common lung CT scan findings are bilateral ground glass opacities.