A combined approach is recommended to treat chronic non-specific low back pain (lumbago), including pharmacological and non-pharmacological methods. Kinesiotherapy non-steroidal anti-inflammatory drugs (NSAIDs) have a high level of evidence in lumbago. includes posture daily motor activity regimen training, complex therapeutic breathing exercises, post-isometric relaxation, other physical exerc...

Eclipta alba Hassk ( Asteraceae ) having important role in the traditional Ayurvedic, Unani systems of holistic health and herbal medicine of the east. Its main active constituents are wedelolactone, demethylwedelolactone . The important pharmacological activities are Hepatoprotective, Antimicrobial, Antinociceptive, Anti-inflammatory, Analgesic, Immunomodulatory, Antiviral and C.N.S. activity....

Chirality is a fundamental property of biological systems and reflects the underlying asymmetry of matter. Interactions of drugs with receptors, enzymes or binding sites have long been known to be stereoselective, and it is increasingly recognized that both pharmacodynamic and pharmacokinetic events contribute to the overall clinically observed stereoselectivity. The pharmacological activity ma...

Several snake venom secreted phospholipases A2 (sPLA2s) including OS2 exert a variety of pharmacological effects ranging from central neurotoxicity to anti-HIV activity by mechanisms that are not yet fully understood. To conclusively address the role of enzymatic activity and map the key structural elements of OS2 responsible for its pharmacological properties, we have prepared single point OS2...

Introduction: Spinal cord injuries are accompanied with significant demyelination of axons and subsequent locomotor dysfunction. To identify the extent of damage following electrolytic lesion of ventrolateral white matter, essential area for initiation of locomotor activity, we assessed demyelination as well as alteration in motor performance. Moreover, the protective effect of estradiol as a c...

Chalcones considered as the precursor of flavonoids and isoflavonoids abundantly found in plants, and have also been shown to display a diverse array of pharmacological activities. This review is complementary to earlier reviews and covers more recent report of antimicrobial activity of chalcones as well as its important role as an intermediate for the synthesis of different synthetic molecules...

Aim: The primary aim of this study is to investigate the effect presence Fibromyalgia(FM) on cardiovascular risk and cardiopulmonary capacity in diabetes mellitus (DM) patients. In addition, prevalence FM DM patients was investigated according American College Rheumatology (ACR) 2016 criteria.
 Material Methods: included 188 premenopausal female with Type 2 DM. physical activity level part...

Pyridazine nucleus exhibited immense pharmacological activities. Pyridazine nucleus is present in various compounds that possess remarkable pharmacological activities. Various pyridazinone compounds have antitumor activity. Some of them pyridazinone derivatives bearing different moieties were exhibited excellent anticancer activity toward human cancer cell lines. They showed remarkable activity...

Background and objectives: Lippia citrodora commonly known as lemon verbena is a species of flowering plant in the verbena family, native to western South America. With its antioxidant effects, it is mostly used in folk medicine to treat anti-inflammatory diseases, and diseases associated with oxidative stress. This review has presented a summary on L. citordora</e...