MUPS Formulation Factors Pellets that are included in MUPS tablets can be uncoated or coated. The drug may be included in the core or as a layer applied to the inert core of the pellet. In addition, the pellets may have one or more layers that may include suitable excipients for modified release such as polymers for enteric coating or polymers for sustained release. Uncoated pellets are made of...

Background & Aims: Losartan is a non-peptide potent antihypertensive agent that acts through blocking angiotensin II receptors. Hyzaar® is a combination product that contains two drugs, losartan and hydrochlorothiazide, used to lower high blood pressure. There are some reports regarding simultaneous measurement of the drugs in pharmaceutical and biological samples which includes HPLC, CE, CEC, ...

BCS class II drugs pose challenging problems in their pharmaceutical product development process because of their low solubility and dissolution rates. They require enhancement in solubility and dissolution rate in their formulation development especially solid dosage forms such as tablets and capsules. Several conventional methods and new emerging technologies have been developed for formulati...

These are additives used to convert pharmacologically active compounds into pharmaceutical dosage forms suitable for administration to patients [1]. Although excipients are the non-active ingredients, they are essential in the successful production of acceptable solid dosage forms such as tablets and powders. For example, the lack of filling materials would make it exceedingly challenging, if n...

Three-dimensional printing (3DP) is a rapid-prototyping technology that uses digital model file to construct an object through layer printing. This novel widely used in aerospace, medicine, architecture and industrial applications. However, the pharmaceutical applications of 3DP remain early stages, industry expected experience revolution 3DP. Herein, recent research progress 3D-printed medicin...

Investigation on natural sources from plants, animals, and microorganisms that produce gums mucilages goes increasing day by to check their pharmaceutical applications. Different have been studied for effects but the use of date palm (Phoenix dactylifera L.) mucilage as a excipient is still under cover. The aim this study was therefore evaluate compare flow property binding ability crude, purif...

Analysis of the sticking problem on xyz tablet using PDCA method at PT. Sunthi Sepuri. Products that have a good level quality will certainly get its own value for consumers. That's why product is measure success product.. Every company must carry out activities in business and every activity has certain goals to be achieved as direction implementation activities. To achieve this goal, it neces...