Since 2004 the European Directive 2001/20/EC concerning the implementation of good clinical practice in the conduct of clinical trials on medicinal products has become operative in Italy (Decreto legislativo 24 giugno 2003, n. 211). It is therefore the intention of the Ministry of Health to obtain through an intelligent application of the recent national decree clear indications on how to condu...

Payers in Europe and North America have embraced generic medicines because of their perceived cost advantages in relation to branded products and the savings they create to health insurance. A robust body of evidence exists to date pointing at savings achieved through genericization. All stakeholders accept that realizing these savings is desirable as health systems face continuous cost pressur...

The present article presents a review of the definitions and methodologies of pharmaceutical dispensing elaborated by the regulating authorities, professional and health organizations in Brazil and abroad and also by some Brazilian authors from the perspective of the technical and philosophical aspects involved. Several dispensing models consider the technical aspects related to the medicines a...