A brief review of studies using X-ray Absorption Spectroscopy (XAS) to investigate homogeneous catalytic reactions in fine chemical and pharmaceutical context since 2010 is presented. The advantages of the techniques over traditional lab-based analytical tools, particularly when NMR spectroscopy fails to deliver mechanistic insights, are summarised using these examples. A discussion on the curr...

Chronic diseases are pressing health systems to introduce reforms, focused on primary care and multidisciplinary models. Community pharmacists have developed a new role, addressing pharmaceutical care and services. Information systems and technologies (IST) will have an important role in shaping future healthcare provision. However, the best way to design and implement an IST for pharmaceutical...

The application of terahertz pulsed spectroscopy to polymorphic, liquid crystalline and amorphous forms of pharmaceutical compounds has been investigated. The different polymorphic forms of carbamazepine and enalapril maleate exhibit distinct terahertz absorbance spectra. In contrast to crystalline indomethacin and fenoprofen calcium, amorphous indomethacin and liquid crystalline fenoprofen cal...

The aim of this study was to assess applicative properties of the produced acc. to own prescription dental anti-inflammatory hydrogel with Carbopol 974P. Ketoprofen pharmaceutical availability was tested from hydrogel with Carbopol 974P and to compare - from hydrogels of similar prescription produced on the base of xanthan gum carboxymethylcellulose sodium salt. Very high pharmaceutical availab...

Psychotropic drugs are an important family of compounds from a medical point of view. Their application in therapy requires methods for the determination in pharmaceutical dosage forms and body fluids. Several methods for their analysis have been reported in the literature. Among the methods, spectrophotometric and electrochemical are very useful for the determination of the drugs. Some of the ...

Rapid and sensitive spectrophotometric method has been developed for the determination of Enalapril in pharmaceutical formulations. The method is based on the complex formation in acidic media (pH 2), using the Tropeolin 00 and hydrochloric acid. The formed complex is extractable with dichloromethane and shows a maximum absorbance at 415 nm, following the Lambert–Beer law in the concentration r...

Ramsey pricing has been proposed in the pharmaceutical industry as a principle to price discriminate among markets while allowing to recover the (fixed) R&D cost. However, such analyses neglect the presence of insurance or the fund raising costs for drug reimbursement. By incorporating these new elements, we aim at providing some building blocks towards an economic theory merging Ramsey pricing...

For the PAT application of microbial monitoring instruments in pharmaceutical field, certain performance features of a detector technology are highly desirable, among them are: (1) real time microbial detection; (2) capability of continuous monitoring of microbial level in the environment; (3) broad detection range of microbes; (4) freedom from sample preparation and (5) ease of operation. To p...

Indian sago starch extracted from Tapioca roots finds its application not only as a food but also numerous commercial applications. In the present review we are discussing concisely the extraction, physiochemical properties, chemical modifications and pharmaceutical applications of Indian sago starch. The sago starch is a cheap, easily available, biodegradable and a versatile polymer. Starch ha...

Currently, because globalization, the pharmaceutical industry is facing enormous challenges to comply with regulatory matters. Reduced patent life and overall decreased profitability of newly discovered drugs are also forcing the pharmaceutical industry to shorten the drug development time with maximum throughput. Therefore, continuous manufacturing (CM) processes via hot melt extrusion (HME) c...