A review of the literature regarding Munchausen syndrome by proxy in relation to allegations of child sexual abuse is presented. Problems in the diagnosis of Munchausen syndrome by proxy in these cases can be the result of a failure to consider that the allegations may be false, legal issues surrounding the child's testimony, and other biases in professional and legal attitudes towards allegati...

Hantaviruses cause 2 zoonotic diseases, hemorrhagic fever with renal syndrome (HFRS) and hantavirus cardiopulmonary syndrome. Infection is usually initiated after inhalation of virus-contaminated rodent excreta. In addition to the zoonotic infection route, growing evidence suggests person-to-person transmission of Andes virus. For this reason, we studied whether saliva from HFRS patients contai...

The article represents the problem of «psychological emotional abuse» a coach, which has negative effect on professional activity. Trainer, like and teacher, inclusions to activity, is characterized by high emotional, psychological ambitions. specificity pedagogical activity coach lies in fact that she will also follow laws intercourse, transferring active interaction. coach's mastery based sev...

1. Stiff-person syndrome (SPS) is an autoimmune disease characterized by muscle rigidity, episodic muscle spasms, as well as continuous cocontraction of agonist and antagonist muscles. 2. Although a criterion for diagnosis of SPS, anti– glutamic acid decarboxylase (anti-GAD) antibodies can be negative in up to 40% of patients. In absence of antibodies, characteristic EMG findings of continuous ...

BACKGROUND The stiff person syndrome (SPS) is a rare disorder characterized by muscular rigidity and stiffness. CASE PRESENTATIONS We describe an SPS patient presenting with longstanding fatigue and electrophysiological evidence of presynaptic neuromuscular transmission defect, who responded to administration of pyridostigmine. In contrast, no electrophysiolgical evidence of neuromuscular tra...

Stiff-person syndrome (SPS) is a disabling central nervous system disorder characterized by muscle stiffness, rigidity, and superimposed painful spasms affecting axial and proximal limb muscles. Electromyography shows continuous motor unit activity in axial muscles. There is strong evidence of an autoimmune pathogenesis for SPS. High levels of antibodies against the 65-kD isoform of glutamic ac...

Finding the underlying etiology of transverse myelitis (TM) can be challenging, as several disorders, including multiple sclerosis (MS), neuromyelitis optica, acute disseminated encephalomyelitis, postvaccine myelitis, Sjögren disease, neurosarcoidosis, infectious myelopathies, or idiopathic TM, may be causative. Paraneoplastic myelopathy, another differential diagnosis, is associated with a br...

BACKGROUND Anxiety is a heterogeneous behavioral domain playing a role in a variety of neuropsychiatric diseases. While anxiety is the cardinal symptom in disorders such as panic disorder, co-morbid anxious behavior can occur in a variety of diseases. Stiff person syndrome (SPS) is a CNS disorder characterized by increased muscle tone and prominent agoraphobia and anxiety. Most patients have hi...

Autoantibodies to the 65-kDa isoform of glutamate decarboxylase GAD65 (GAD65Ab) are strong candidates for a pathological role in Stiff-Person syndrome (SPS). We have analyzed the binding specificity of the GAD65Ab in serum and cerebrospinal fluid (CSF) of 12 patients with SPS by competitive displacement studies with GAD65-specific rFab-derived from a number of human and mouse mAbs specific for ...