نتایج جستجو برای: perrys mouse tail
تعداد نتایج: 329222 فیلتر نتایج به سال:
STUDY DESIGN Measurement and normalization of disc geometry parameters for several animal models used in disc research. OBJECTIVES To compare normalized values of disc geometry to the human disc geometry to aid in the selection and interpretation of animal model studies. SUMMARY OF BACKGROUND DATA Animal models are widely used to study intervertebral disc degeneration and to evaluate disc t...
Recombinant adeno-associated virus (rAAV) vectors stably transduce hepatocytes in experimental animals. Following portal-vein administration of rAAV vectors in vivo, single-stranded (ss) rAAV genomes become double stranded (ds), circularized, and/or concatemerized concomitant with a slow rise and, eventually, steady-state levels of transgene expression. Over time, at least some of the stabilize...
A common method of genotyping mice is via tissue obtained from tail biopsies. However, there is no available information on the temporal development of sensory neurons in the tail and how their presence or absence might affect the age for performing tail biopsies. The goals of this study were to determine if afferent sensory neurons, and in particular nociceptive neurons, are present in the coc...
A central feature of the tetrapod body plan is that two pairs of limbs develop at specific positions along the head-to-tail axis. However, the potential to form limbs in chick embryos is more widespread. This could have implications for understanding the basis of limb abnormalities. Here we extend the analysis to mouse embryos and examine systematically the potential of tissues in different reg...
We established the mutant mouse line, B6;CB-SktGtAyu8021IMEG (SktGt), through gene-trap mutagenesis in embryonic stem cells. The novel gene identified, called Sickle tail (Skt), is composed of 19 exons and encodes a protein of 1352 amino acids. Expression of a reporter gene was detected in the notochord during embryogenesis and in the nucleus pulposus of mice. Compression of some of the nuclei ...
Thrombocytes, also known as platelets, are crucial in maintaining the balance between blood clotting. Platelet hyperactivity and oxidative stress primary factors contributing to cardiovascular complications. Antithrombotic therapy remains one of most effective treatments, but various potential side effects hinder its effectiveness, including risk haemorrhage. Intense research has been conducted...
Mechanical stretching changes crosslinking and glycation levels in the collagen of mouse tail tendon
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