The settlement rate and pore water pressure dissipation are mainly controlled by the permeability of soil. Both laboratory field tests show that is varied during loading consolidation process. It known process accompanied decrease in void ratio which leads to coefficient permeability. importance on time needs be investigated.This paper takes into account change studies its effect characteristic...

In the last 3 years there has been a huge increase in the use of pore-scale modeling to study multiphase flow and transport in porous media. Starting from single pore models of fluid arrangements, computations of relative permeability, interfacial area, dissolution rate and many other physical properties have been made. Combined with a realistic description of the pore space, predictive modelin...

The data presented in this article are related to the article titled "Molecular Dynamics as a tool for in silico screening of skin permeability" (Rocco et al., 2017) [1]. Knowledge of the confidence interval and maximum theoretical value of the correlation coefficient r can prove useful to estimate the reliability of developed predictive models, in particular when there is great variability in ...

Blood-brain barrier integrity during cardiopulmonary resuscitation may be important because of the potential effects of adrenergic agonists administered during arrest on cerebral metabolism and the cerebral vasculature. As an index of blood-brain barrier permeability to small molecules, we measured the brain uptake of [14C]alpha-aminoisobutyric acid during a 10-minute period in 25 anesthetized ...

RATIONALE In chronic heart failure, the lung endothelial permeability response to angiotensin II or thapsigargin-induced store depletion is ablated, although the mechanisms are not understood. OBJECTIVES To determine whether the ablated permeability response to store depletion during heart failure was due to impaired expression of store operated Ca2+ channels in lung endothelium. METHODS He...

The fluorescein kinetics in the vitreous was simulated with a computer to consider several factors such as permeability of the blood-retinal barrier, outward active transport, plasma fluorescein dynamics, diffusion of fluorescein in the vitreous, and fluorescein leakage from the blood-aqueous barrier. Kinetic vitreous fluorophotometry was performed in normal individuals to estimate the inward a...

This study was undertaken to determine in vivo permeability coefficients for fluoroquinolones and to assess its correlation with the permeability derived using reported models in the literature. Further, the aim was to develop novel QSPR model to predict corneal permeability for fluoroquinolones and test its suitability on other training sets. The in vivo permeability coefficient was determined...

Vasopressin (VP) increases the water permeability of the toad urinary bladder epithelium by inducing the cycling of vesicles containing water channels to and from the apical membrane of granular cells. In this study, we have measured several functional characteristics of the endosomal vesicles that participate in this biological response to hormonal stimulation. The water, proton, and urea perm...

Measurements of diffusion and partitioning of solutes having molecular weights ranging 180-66 000 in PVA gel membranes with various crosslinking degree were carried out. With increasing solute size or decreasing number of average molecular weight between crosslinks of the membranes, both the solute permeability and partition coefficient decreased. In spite of similar solute sizes, the more hydr...

The method of solute permeability coefficient and solute fluxes appointment for the membrane, based on monitoring of changes of conductivity of electrolyte solutions was presented. It was stated that during mechanical stirring of solutions the coefficient of NaCl permeability for microbial cellulose membrane (Biofill) did not depend on configuration of the membrane system and concentrations of ...