Yazışma Adresi / Address for Correspondence: Kadir Şerafettin Tekgündüz, Atatürk Üniversitesi Tıp Fakültesi, Yenidoğan Hastalıkları, Erzurum, Türkiye. E-posta / E-mail: [email protected] Geliş Tarihi / Received: 26.01.2015 Kabul Tarihi / Accepted: 13.02.2015 ©Telif Hakkı 2015 Türk Pediatri Kurumu Derneği Makale metnine www.turkpediatriarsivi.com web adresinden ulaşılabilir. ©Copyright 20...

Proliferative verrucous leukoplakia (PVL) is a rare oral leukoplakia and has four features such as chronic proliferation, multiple occurrences, refractoriness to treatment and high rate of malignant transformation. As mentioned above, most PVL cases processed to malignancy over many years, sometimes 20 years. However, this report described a case of rapid progress, which had malignant transform...

Drs Cooke and Morgan have shown in a double blind trial that ethamsylate seemed to reduce the incidence of periventricular haemorrhage.' Although this is of great interest, no confirmation of these results is available so far. Yet Delandale Laboratories are already advertising ethamsylate as the drug to prevent periventricular haemorrhage in the newborn infant. In the past similar effects, clai...

OBJECTIVES To measure both fractional anisotropy (FA) values in the corticospinal tracts (CSTs) and volume of the thalami in preterm infants with cystic periventricular leukomalacia (c-PVL) and to compare these measurements with control infants. STUDY DESIGN Preterm infants with c-PVL and controls with magnetic resonance imaging data acquired between birth and term equivalent age (TEA) were r...

We report neurologic damage in twins that was associated with twin-twin transfusion syndrome. Intracranial hemorrhage, detected prenatally, was seen in the larger twin , and periventricular leukomalacia was identified on the first day of life in the smaller twin . Recognition of fetal intracerebral hemorrhage on prenatal sonograms is uncommon; it has been reported only three times (1-3] . The p...

Introduction:DCC is a common practice with several benefits. The benefits of DCC are decreased risk anemia, less incidence periventricular leukomalacia, NEC. This study tries to compare the effect different duration delayed cord clamping on serum bilirubin, hematocrit and hemodynamic status neonate. Material method:A prospective was done over span one year comprising 150 full term neonates. Aft...

OBJECTIVE The aim of this study is to determine whether the cystic periventricular leukomalacia (cPVL) detection rate differs between imaging studies performed at different time points. DESIGN We retrospectively reviewed the prospectively collected data of 31,708 infants from the NICHD Neonatal Research Network. Inclusion criteria were infants < 1,000 g birth weight or < 29 weeks' gestational...

Twin-twin transfusion syndrome (TTTS) complicates approximately 1 in 5 of all monochorionic, diamniotic twin pregnancies. If of early onset and untreated, severe TTTS is associated with a dismal prognosis, with perinatal mortality rates exceeding 90%. The most controversial issue regarding the optimal treatment of TTTS has centered on the use of amniocentesis or laser until the first and only r...

The cerebral white matter is vulnerable to injury in very preterm infants (born prior to 30 weeks gestation), resulting in a spectrum of lesions. These range from severe forms, including cystic periventricular leukomalacia and periventricular hemorrhagic infarction, to minor focal punctate lesions. Moderate to severe white matter injury in preterm infants has been shown to predict later neurode...

Ferrostatin-1 (Fer-1) inhibits ferroptosis, a form of regulated, oxidative, nonapoptotic cell death. We found that Fer-1 inhibited cell death in cellular models of Huntington's disease (HD), periventricular leukomalacia (PVL), and kidney dysfunction; Fer-1 inhibited lipid peroxidation, but not mitochondrial reactive oxygen species formation or lysosomal membrane permeability. We developed a mec...