In this study, leptin/BMI ratio in serum and peritoneal fluid and gene expression of leptin and long form leptin receptor (OB-RL) were assessed in eutopic and ectopic endometria of women with endometriosis and controls. Increased serum leptin/BMI ratio was found in endometriosis patients. Leptin and OB-RL gene expression was significantly higher in ectopic versus eutopic endometrium of patients...

BACKGROUND Emerging evidence suggests a potential role for ubiquitous environmental contaminants in the physiopathology of endometriosis. Di-(2-ethylhexyl)-phthalate (DEHP), the most commonly used plasticizer in flexible polyvinylchloride (PVC) formulations, is a widespread environmental contaminant with potentially adverse effects on fertility in animal models. In the present study, we tested ...

OBJECTIVE Our aim was to characterize peritoneal cytokine profiles in patients with infertility, with and without endometriosis, to illuminate potential differences in immune profiles that may reflect mechanistic differences between these two patient populations. DESIGN Cross-sectional study. SETTING University hospital and research center. PATIENT(S) Women undergoing laparoscopy for infe...

Endometriosis with extensive deep affectation needs a targeted MR study for an accurate diagnosis and treatment planning. The reported patient had affectation of the three compartments, with solid invasive masses, predominantly fibrous. Since laparoscopy provides limited information on the sub peritoneal extent and presence of endometriotic lesions in areas hidden by adhesions, the non-invasive...

BACKGROUND To report a placenta percreta in a 7-week gestational rudimentary noncommunicating uterine horn pregnancy. METHODS A 28-year-old woman with no complaints presented with a rudimentary uterine horn pregnancy at 7-weeks gestation. The diagnosis was suspected by ultrasonography and diagnosed by laparoscopy. Laparoscopic excision of the rudimentary uterine horn and ipsilateral salpingec...

Endometriosis is one of the most common gynaecologic diseases in women of reproductive age. It is characterized by the presence of endometrial tissue outside the uterine cavity. The women affected suffer from pelvic pain and infertility. The complex etiology is still unclear and it is based on three main theories: retrograde menstruation, coelomic metaplasia, and induction theory. Genetics and ...

Objectives: To compare between hysterosalpingography (HSG) and laparoscopic findings in patients tested for infertility thereby to determine the significance of latter examination. Methods: This was a descriptive study performed two Gynecology departments Dakar (Senegal). Included were 84 with suspicious tubal-infertility who underwent HSG followed by laparoscopy. The Kappa (K) statistics used ...

OBJECTIVE To evaluate the rate of intrinsic ureteral endometriosis in patients presenting with severe ureteral endometriosis. DESIGN Observational study between June 1992 and December 2007. SETTING University tertiary referral center. PATIENT(S) Twenty-nine patients presenting deeply infiltrating endometriosis (DIE) with severe ureteral endometriosis. Severe ureteral endometriosis was def...

BACKGROUND Endometriosis is a highly prevalent, benign disease in which the angiogenic, fibrinolytic and metalloproteinase (MMP) systems may be implicated. The objective of this study is to analyse mRNA expression and protein levels of several angiogenic factors and to correlate them with several components of the fibrinolytic and MMP systems in samples from 71 women with endometriosis and 50 c...

Endometriosis is a benign reproductive disorder distinguished by chronic inflammation and anomalous progress of stromal cells glands outside the uterus. Though etiology endometriosis still matter debate, immuneinflammatory mediators are thought to play major role. Macrophage infiltration proinflammatory intermediaries in peritoneal environment milieu impact ovarian, uterine function pelvic morp...