Burkitt lymphoma is a fast-growing high grade B-cell neoplasm that rarely affects adults. Three clinical variants are described in the World Health Organization classification: endemic, sporadic, and immunodeficiency-associated. The non-endemic form typically presents as an abdominal mass in children. Symptoms usually occur due to mass effect or direct intestinal involvement. We describe a very...

Peritoneal carcinomatosis is the most frequent pattern of metastasis and recurrence in patients with gastric cancer, and the prognosis of those patients with peritoneal metastasis is extremely poor. Once peritoneal metastasis is formed, it is extremely difficult to overcome. EIPL (extensive intraoperative peritoneal lavage) is a quite useful and practical adjuvant surgical technique for the gas...

PURPOSE The aim of this study was to analyse feasibility, morbidity and outcome of repeat complete cytoreductive surgery (CRS) plus hyperthermic intraperitoneal chemotherapy (HIPEC). CRS combined with HIPEC is becoming the gold standard treatment for resectable peritoneal carcinomatosis in highly selected patients. As yet treatment of isolated peritoneal recurrence with iterative CRS and HIPEC ...

Introduction Cytoreductive surgery combined with hyperthermic intraperitoneal chemotherapy improves the prognosis of selected patients, in particular those with appendiceal and colon carcinoma (1). At least one third of all patients is still alive after treatment. Main prognostic factors are completeness of cytoreduction and the tumor volume expressed by the Peritoneal Cancer Index (should be l...

Peritoneal metastasis is a significant clinical challenge; life expectancy following diagnosis is usually very short. Surgical cytoreduction with HIPEC is being used with increasing frequency in selected patients; most outcome data have shown that prolonged median survivals can be observed in selected patients. This review summarizes the published data related to outcome and quality of life aft...

Pseudomyxoma peritonei (PMP) is classified into pathologically and prognostically distinct categories, such as disseminated peritoneal adenomucinosis (DPAM) and peritoneal mucinous carcinomatosis. There is overwhelming evidence that DPAM arises from a mucinous adenoma of the appendix. The one exception to this is the presentation of a mature ovarian cystic teratoma as PMP where the appendix is ...

Background Peritoneal carcinomatosis is a frequent evolution of gastrointestinal and gynecologic malignancy and it has been regarded as a lethal clinical entity. Treatment options for these patients have improved significantly in the past few years. CytoReductive Surgery (CRS) plus Hyperthermic IntraPEritoneal Chemotherapy (HIPEC) is an aggressive and promising treatment for patients with perit...

The primitive neuroectodermal tumors (PNETs) produce metastases in the basicranial axis. Extracranial metastases are infrequent and occur by dissemination through the cerebrospinal fluid (CSP). Sixty two cases of peritoneal carcinomatosis have been reported to date as due to a ventriculo-peritoneal shunt (VPS), four of them by pineoblastoma. We present the case of a pineoblastoma showing this e...

BACKGROUND This study investigates the pharmacokinetics and toxicity of cisplatin, admininistered by a new semi-closed hyperthermic peritoneal perfusion (HPP) technique to patients with peritoneal carcinomatosis. MATERIALS AND METHODS After surgical cytoreduction, 12 patients were given cisplatin 100 mg/m2 (CDDP), introduced into the HPP circuit for 60 min at 41.7 degrees C and 1200 ml/min fl...

AIM To review the published literature analyzing the role of intraperitoneal chemotherapy in gastric cancer. MATERIAL OF STUDY Peritoneal dissemination is a well recognized and important component of disease progression in gastric cancer. Considering that involvement of the peritoneal surface can be anticipated in a large number of patients who present with an advanced gastric cancer, researc...