نتایج جستجو برای: peripheral blood mononuclear cell
تعداد نتایج: 2306671 فیلتر نتایج به سال:
High levels of resistance to challenge with human immunodeficiency virus type 1 SF162 were observed in animals engrafted with peripheral blood mononuclear cells of four long-term nonprogressors (LTNPs). Resistance was abrogated by depletion of CD8(+) T cells in vivo and was observed only in LTNPs with proliferative responses to p24. In a subgroup of nonprogressors, CD8(+) T cells mediated restr...
, and the mean (Ϯ2 SD) was computed and then converted to the original units. True gaussian distributions are shown superimposed in panels A and B of Fig. 1 for comparison with the original data. Palmitic acid had a mean oxidation rate of 46 pmol ⅐ min Ϫ1
The quantitative and qualitative behavior of hemorheologic factors both at rest and after treadmill exercise in 30 male patients with stage II peripheral vascular disease compared with 20 sex- and age-matched healthy controls have been studied. The aim of our study was to identify functional rheologic markers for peripheral vascular disease. At rest, whole blood viscosity (corrected for hematoc...
The quantitative and qualitative behavior of hemorheologic factors both at rest and after treadmill exercise in 30 male patients with stage II peripheral vascular disease compared with 20 sexand age-matched healthy controls have been studied. The aim of our study was to identify functional rheologic markers for peripheral vascular disease. At rest, whole blood viscosity (corrected for hematocri...
Sarday, M ay 6, 2017 PURPOSE: We recently developed a serum-free, ex vivo cell expansion system called Mononuclear Cell Quality and Quantity Control Culture System (MNC-QQc), using peripheral blood mononuclear cells (MNCs), to increase the number and the vasculogenic property of endothelial progenitor cells (EPCs) for enhanced vasculogenesis and tissue regeneration from a small amount of periph...
BACKGROUND In our efforts to develop novel effective treatment regimens for multiple myeloma we evaluated the potential benefits of combining the immunomodulatory drug lenalidomide with daratumumab. Daratumumab is a novel human CD38 monoclonal antibody which kills CD38+ multiple myeloma cells via antibody-dependent cell-mediated cytotoxicity, complement-dependent cytotoxicity and apoptosis. D...
Homologous restriction factor (HRF) is a 65-kDa membrane protein that inhibits transmembrane channel formation by the membrane-attack complex of complement and by the complement component C9-related cytolytic lymphocyte protein. Stimulation of resting peripheral human lymphocytes with the anti-CD3 monoclonal antibody OKT3 has been shown to induce cytotoxicity in the CD8+ subpopulation. As demon...
Background The Cancer Immunotherapy Trials Network has initiated several clinical trials utilizing T cell growth factors such as IL-15 and IL-7. In support of these trials, we have developed and conducted precision testing of a 12-color flow cytometric assay to characterize the surface markers present on T cells in fresh whole blood and among cryopreserved peripheral blood mononuclear cells (PB...
Using an ultrasensitive assay involving the PCR, we have examined the frequency of a follicular lymphoma-associated translocation in peripheral blood from 132 individuals, most of whom were healthy blood donors. This translocation occurs between the bcl-2 proto-oncogene and the JH gene region and prolongs the life of lymphocytes. At a level of sensitivity of 1 translocation-bearing cell per 5 x...
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