Inflammation and neuroprotective strategies in the immature brain after hypoxic-ischemic brain injury Pernilla Svedin, 2008, Perinatal Center, Department of Physiology, Institute of Neuroscience and Physiology, University of Gothenburg, Box 432, 405 30 Göteborg Sweden Perinatal brain injury, as a result of hypoxia-ischemia (HI) or infection/HI, is a major cause of acute mortality and neurologic...

Hepatitis B virus (HBV) and hepatitis C virus (HCV) are acquired by contaminated blood product exposure, sexual activity, perinatal transmission are also important source of infection [1]. Women during childbearing age have a 1 to 2% incidence of chronic HCV infection, with higher rates in those with risk factors like patients undergone hemodialysis [2]. Pregnancy in patients with chronic HBV o...

BACKGROUND Perinatal and horizontal are the common modes of transmission of hepatitis-B virus in children. CASE CHARACTERISTICS Two mother-child pairs with children having received multiple blood transfusions in past. OBSERVATION Both the mothers developed acute hepatitis-B infection whereas children were demonstrated to be having chronic infection with hepatitis-B. OUTCOME One mother cle...

OBJECTIVE To correlate clinical variables (gestational age, severe pregnancy-induced hypertension, gestational diabetes mellitus, history of previous cesarean sections, fetal distress, perinatal mortality, postpartum anemia, Apgar score < or = 3 at 1 minute and < or = 7 at 5 minutes, and instrumental delivery) with postpartum endometritis (PPE) and wound infection. METHODS Descriptive cross-s...

Effective prevention strategies have reduced the risk of perinatal transmission of human immunodeficiency virus (HIV) infection to less than 1% to 2% in the United States, but failures to fully implement these strategies result in continued preventable infant HIV infections. In addition, the increasing number of sexually acquired HIV infections in adolescents underscores the important role of t...

Hepatitis B virus (HBV) and hepatitis C virus (HCV) are acquired by contaminated blood product exposure, sexual activity, perinatal transmission are also important source of infection [1]. Women during childbearing age have a 1 to 2% incidence of chronic HCV infection, with higher rates in those with risk factors like patients undergone hemodialysis [2]. Pregnancy in patients with chronic HBV o...

BACKGROUND In trials designed to estimate rates of perinatal mother to child transmission of HIV, HIV assays are scheduled at multiple points in time. Still, infection status for some infants at some time points may be unknown, particularly when interim analyses are conducted. METHODS Logistic regression models are commonly used to estimate covariate-adjusted transmission rates, but their met...

OBJECTIVE To determine the association between amniotic fluid index (AFI) and perinatal outcomes in preterm premature rupture of membranes (PPROM). METHOD A retrospective cohort study was conducted between 2008 and 2012. 86 pregnant women were included, with a diagnosis of PPROM and gestational age from 24 to 35 weeks. Women who presented hypertensive disorders, diabetes, fetuses with birth d...

Placental malaria is recognized as a common complication of malaria in pregnancy in areas of stable transmission, and, as a consequence, serious health problems arise for the mother and especially her baby [1]. Although malaria in pregnancy is a major factor associated with adverse perinatal outcome, the link between malaria and perinatal morbidity/mortality is less clear in areas with stable e...

Cytomegalovirus (CMV) infection is the most common congenital infection, affecting 0.4% to 2.3% newborns. Most of them are asymptomatic at birth, but later 10% develop handicaps, mainly neurological disturbances. Our aim was to determine the prevalence of CMV shed in urine of newborns from a neonatal intensive care unit using the polymerase chain reaction (PCR) and correlate positive cases to s...