Background. Cilazapril is a novel angiotensin converting enzyme inhibitor with antiproliferative effects in the rat model after balloon injury. Methods and Results. We conducted a randomized, double-blind placebo-controlled trial to assess the effect of cilazapril in angiographic restenosis prevention after percutaneous transluminal coronary angioplasty (PTCA). Patients received cilazapril 2.5 ...

Seventy-five patients 36 to 68 years of age were studied after undergoing successful single-vessel percutaneous transluminal coronary angioplasty (PTCA). In all cases exercise tests (ETs) were made prior to the procedure and 2 to 4 days and 6 months thereafter. Angiographic controls were performed on patients with positive ET. Both early and late ET carried out after dilatation lasted significa...

Fifteen patients undergoing routine follow-up angiography 5 months after successful percutaneous transluminal coronary angioplasty (PTCA) without angina and with normal exercise thallium scintigraphy were selected for analysis. The coronary flow reserves of these patients were compared with those of 24 patients with angiographically normal coronary arteries to establish whether PTCA can restore...

BACKGROUND Because ascending aortic pressure has a greater effect on coronary perfusion during diastole than systole, we hypothesized that a high coronary diastolic-to-systolic pressure ratio prevents coronary lesions from restenosing after percutaneous transluminal coronary angioplasty (PTCA) and that ascending aortic pulsatility relative to mean pressure is higher in patients with restenosis ...

Inappropriate percutaneous transluminal coronary angioplasty of the anterior descending artery was avoided in a 52-year-old woman when the intracoronary administration of glyceryl trinitrate immediately before the angioplasty disclosed the organic component of the supposedly fixed, critical (80%) stenosis to be less than 50% of the lumen diameter. The spastic component of the stenosis had not b...

BACKGROUND Despite, increasing number of percutaneous transluminal coronary angioplasty (PTCA) being performed, there is a paucity of Indian studies on the psychological effects of PTCA. Aim. To study the relation of anxiety, depression, and health related quality of life with outcome after PTCA. METHODS A total of 35 patients undergoing PTCA were included in the present project with their in...

Intracoronary urokinase was used to treat flow-limiting intracoronary thrombus accumulation that complicated successful percutaneous transluminal coronary angioplasty (PTCA) during acute ischemic syndromes in 48 patients who were followed up through the acute phase of their illness. The study group comprised 10 patients with unstable angina pectoris, 18 patients with an evolving acute myocardia...

By 2000, more than 1 202 000 percutaneous and 519 000 surgical revascularization procedures were being performed annually in the United States.1 The 3 potential reasons to recommend myocardial revascularization are (1) to alleviate symptoms of myocardial ischemia, (2) to reduce the risks of future mortality, and (3) to treat or prevent morbidities such as myocardial infarction, arrhythmias, or ...

OBJECTIVES This study sought to compare the outcome of percutaneous transluminal coronary angioplasty (PTCA) (n = 834) and coronary artery bypass graft surgery (CABG) (n = 1805) in diabetic patients with multivessel coronary disease from an observational database. BACKGROUND There is concern about selection of revascularization in diabetic patients with multivessel coronary artery disease. ...