BACKGROUND Pectin-rich agricultural wastes potentially represent favorable feedstocks for the sustainable production of alternative energy and bio-products. Their efficient utilization requires the conversion of all major constituent sugars. The current inability of the popular fermentation host Saccharomyces cerevisiae to metabolize the major pectic monosaccharide D-galacturonic acid (D-GalA) ...

A new class of surface-structured RO membranes was developed with a hydrophilic brush layer of terminally anchored polymer chains resulting in fouling resistant membranes of low mineral scaling propensity and high permeability. The approach is based on free-radical graft polymerization of a suitable monomer, onto the active polyamide (PA) layer of a thin film composite (PA-TFC) membrane, post-s...

The variable composition of secondary organic aerosols (SOA) contributes to the large uncertainty for predicting radiative forcing. A better understanding of the reaction mechanisms leading to aerosol formation such as for the photochemical reaction of aqueous pyruvic acid (PA) at λ ≥ 305 nm can contribute to constrain these uncertainties. Herein, the photochemistry of aqueous PA (5-300 mM) con...

Phenylacetic acid (PA), a phytotoxic product of the bacteria accompanying the virulent nematode isolate OKD-3 was detected in the callus of Pinus thunbergii after inoculation with the nematode. The amount of PA detected was large enough to induced the formation and accumulation of benzoic acid (BA) and its conjugates in the callus. These results further support the hypotheses that PA is the pat...

Objective: Some of the adverse effects of aspirin including peptic ulcers, gastrointestinal bleeding and aspirin resistance compelled researchers to find a suitable alternative with fewer adverse effects. In this clinical trial, we aimed to find the effective antiplatelet dose of garlic. Materials and Methods: This randomized controlled clinical trial (RCT) was conducted on 62 healthy volunteer...

BACKGROUND Abnormalities in fatty acid metabolism and membrane fatty acid composition play a part in a wide range of neurodevelopmental and psychiatric disorders. Altered fatty acid homeostasis as a result of insufficient dietary supplementation, genetic defects, the function of enzymes involved in their metabolism, or mitochondrial dysfunction contributes to the development of autism. OBJECT...

Membrane filtration technology has attracted extensive attention in academia and industry due to its advantages of eco-friendliness related environmental protection high efficiency. Polyamide thin-film composite nanofiltration (PA TFC NF) membranes have been widely used their separation performance. Non-acid-resistant PA NF face tremendous challenges an acidic environment. Novel relatively acid...

We have investigated possible roles of RhoA and H2O2 in the elevation of intracellular Ca2+ ([Ca2+]i) by phosphatidic acid (PA) in Rat-2 fibroblasts. PA induced a transient elevation of [Ca2+]i in the presence or absence of EGTA. Lysophosphatidic acid (LPA) also increased [Ca2+]i, but the sustained Ca2+ response was inhibited by EGTA. LPA stimulated the production of inositol phosphates, but PA...

Grape pomace is one of the main by-products in wine industry and contains some high-added-value compounds, such as polysaccharides. Considering wide application possibilities polysaccharides food industry, revalorization grape to extract presents itself an opportunity for by-product management. Therefore, aim this study was characterize polysaccharide extracts obtained from different white vari...

Adult Refsum disease (ARD) is associated with defective alpha-oxidation of phytanic acid (PA). omega-Oxidation of PA to 3-methyl-adipic acid (3-MAA) occurs although its clinical significance is unclear. In a 40 day study of a new ARD patient, where the plasma half-life of PA was 22.4 days, omega-oxidation accounted for 30% initially and later all PA excretion. Plasma and adipose tissue PA and 3...