Peanut allergy is life threatening health concern that caused by allergenic proteins termed as Arachis hypogea present in peanut. The most fatal allergic reaction to peanuts anaphylaxis harmful the individuals who are peanut allergens. Sometimes, traces of allergens contamination also occurred during food processing. Hence, it very much important detect allergen products and our proposed study ...

Epicutaneous immunotherapy is a developing technique, aiming at desensitizing patients with food allergy with less risks that oral ingestion or injection could generate. Several clinical trials have been performed and are currently running, in milk and peanut allergy, assessing the safety of the technique and its efficacy. Preclinical models indicate a major role in the mechanisms of desensitiz...

ance to peanuts. J. Clin. Invest. 111:1065–1072. doi:10.1172/JCI200316142. 7. Cohen, S.B., Webb, L.M., and Feldmann, M. 1996. The method of deriving human T-cell clones alters the proportion of IL-10-producing cells. Immunology. 87:343–347. 8. Demeure, C.E., et al. 1995. Human naive CD4 T cells produce interleukin-4 at priming and acquire a Th2 phenotype upon repetitive stimulations in neutral ...

Diverse therapeutic strategies for food allergy are under investigation including food allergen-specific and nonspecific approaches. Allergen-specific approaches include immunotherapy with native food allergens, immunotherapy with mutated recombinant allergens, and diets containing extensively heated milk or egg. Native allergen immunotherapy can be administered via oral, sublingual, subcutaneo...

The increasing use of lupin in food processing poses a problem of potential (cross-)allergic reactions. To evaluate the prevalence of sensitization to lupin in comparison to that of other legumes skin prick tests were performed with lupin, pea, peanut, and soybean in atopic (n = 81) and non-atopic (n = 102) German adults. Of these 183 subjects, 20 subjects had to be excluded due to invalid skin...

BACKGROUND Allergy to cow's milk increases the risk of sensitization to other foods in young children. OBJECTIVES We sought to evaluate the effect of early epicutaneous immunotherapy (EPIT) on further sensitization to peanut or house dust mite (HDM) in a murine model of sensitization to cow's milk. METHODS BALB/c mice orally sensitized to milk were epicutaneously treated with a Viaskin patc...

BACKGROUND Food allergy to lupine has frequently been reported in patients allergic to peanut or soy, and cross-reactivity between these legumes is known. Moreover, respiratory allergy to lupine has been described after inhalation, mostly at workplaces. Our aim was to study the frequency of lupine sensitization in European bakers with suspected bakers' allergy. Furthermore, associations between...

BACKGROUND The botanical relation between grass and cereal grains may be relevant when diagnosing food allergy to cereals. The aim was to investigate the diagnostic specificity of skin prick test (SPT) and specific immunoglobulin E (sIgE) tests to cereals and peanut in grass pollen allergic subjects without history of, and clinically reactions to foods botanically related to grass. METHODS 70...

In a landmark collaborative action, 10 international medical professional organizations, 2 among them not being allergistimmunologist based (the American Academy of Pediatrics and the Society for Pediatric Dermatology), created a “Consensus communication” suggesting that the approaches taken in the Learning Early About Peanut (LEAP) trial should be actualized for clinical care “in more diverse ...