OBJECTIVE(S) Lichen Planus is a common disease with unknown etiology which affects the skin and mucosa. Recent studies have focused on the possible role of the virus in the pathogenesis of Lichen Planus. The purpose of this study was to determine the association between the human T-cell lymphotropic virus type 1 and Lichen Planus. MATERIALS AND METHODS This case control study was conducted on...

IMPORTANCE Lichen planus is an autoimmune inflammatory dermatosis that typically affects the skin but can also involve the stratified squamous epithelium of the external auditory canals and tympanic membranes. Here we report our experience with the clinical presentation, diagnosis, and management of otic lichen planus. OBSERVATIONS We retrospectively reviewed medical records from January 1, 2...

Lichen planus of the male genitalia presents as multiple violaceous papules or discrete annular lesions on the glans or shaft of the penis. In female patients, whitish striae or "leukoplakia-like" patches are occasionally observed on the vestibulum or labia minora and bluish-white papules in the anal cleft or around the anus. Signs of lichen planus elsewhere on the body may be absent. As has be...

N-acylethanolamines (NAEs) involve a family of lipid molecules existent in animal and plant, with N-palmitoylethanolamide (PEA) that arouses great attention owing to its anti-inflammatory, analgesic and neuroprotective activities. Because PEA is produced on demand and exerts pleiotropic effects, the modulation of specific amidases for NAEs (and in particular NAE-hydrolyzing acid amidase NAAA, w...

Lichen planus pigmentosus-inversus (LPP-inversus) is an extremely rare variant of lichen planus (LP), and only a few cases have been reported. Its course is characterized by exacerbations and remissions, and it is known to be more chronic than classical LP is. We report two cases of LPP-inversus and offer the suggestion that LPP-inversus may originate from LP of flexural areas.

We present the case of a 72-year-old Caucasian woman with frontal fibrosing alopecia of one year's duration. Eighteen months later, she presented with sudden hyperpigmentation on the submental area, neck and upper chest. Histopathological examination was consistent with lichen planus pigmentosus. This is the report of a unique case of a FFA and extrafacial lichen planus pigmentosus.

Lichen planus is an inflammatory, mucocutaneous disease that in addition to the skin involves oral mucosa in about 60-70 % of cases. In recent years, several reports have supposed a relationship between oral lichen planus (OLP) and chronic liver disease, especially hepatitis C (HCV). Here we present an extensive review of the literature in English that examines the association between HCV and OLP.

in 1996 grinspan et al presented the association between primary hypertension and diabetes mellitus as grinspan syndrome. through various studies, researchers have noticed that epidermal lichen planus cells show enzymatic disorders as well as defective carbohydrate expression. therefore, it was assumed that there is a relationship between cells and hormones in metabolic actions. besides, some r...

BACKGROUND AND AIMS Oral lichen planus (OLP) is a common chronic mucocutaneous disease. Patients with atrophic and erosive lichen planus often have symptoms of soreness and need proper treatment. The main therapy of OLP has been the administration of topical or systemic corticosteroids. Potent topical corticosteroids have been increasingly prescribed in the treatment of erosive lichen planus. T...