نتایج جستجو برای: pde های بیضوی

تعداد نتایج: 486730  

Journal: :Graphical Models 2005
Haixia Du Hong Qin

PDE surfaces, which are defined as solutions of partial differential equations (PDEs), offer many modeling advantages in surface blending, free-form surface modeling, and specifying surface s aesthetic or functional requirements. Despite the earlier advances of PDE surfaces, previous PDE-based techniques exhibit certain difficulties such as lack of interactive sculpting capabilities and restrai...

Journal: :Clinical cancer research : an official journal of the American Association for Cancer Research 2015
Haishan Huang Xiaofu Pan Honglei Jin Yang Li Lin Zhang Caili Yang Pei Liu Ya Liu Lili Chen Jingxia Li Junlan Zhu Xingruo Zeng Kai Fu Guorong Chen Jimin Gao Chuanshu Huang

PURPOSE The carcinogenic capacity of B[a]P/B[a]PDE is supported by epidemiologic studies. However, the molecular mechanisms responsible for B[a]P/B[a]PDE-caused lung cancer have not been well investigated. We evaluated here the role of novel target PHLPP2 in lung inflammation and carcinogenesis upon B[a]P/B[a]PDE exposure. EXPERIMENTAL DESIGN We used the Western blotting, RT-PCR, [(35)S]methi...

2017
Teresa Röhrig Olga Pacjuk Silvia Hernández-Huguet Johanna Körner Katharina Scherer Elke Richling

Background: Phosphodiesterases (PDEs) play a major role in the regulation of cyclic adenosine monophosphate (cAMP)- and cyclic guanosine monophosphate (cGMP)-mediated pathways. Their inhibitors exhibit anti-inflammatory, vasodilatory and antithrombotic effects. Therefore, consumption of foods with PDE-inhibiting potential may possess beneficial influence on the risk of cardiovascular diseases. ...

Journal: :Acta neurobiologiae experimentalis 1975
P Uzunov V Petkov S Stancheva

Essential differences in the degree of papaverine [5 x 10(-5) M]- and theophylline [1 x 10(-3) M]-induced inhibition of cyclic nucleotide phosphodiesterase (PDE) were found in homogenates from different structures of the CNS as well as from different organs of male albino rats. Both inhibitors of PDE showed a mosaic pattern of their inhibitory effects on the enzyme activity of the brain structu...

Journal: :The Journal of General Physiology 1986
S Kawamura M Murakami

The possible involvement of phosphodiesterase (PDE) activation in phototransduction was investigated in gecko photoreceptors by comparing the in situ PDE activity with the photoreceptor potential. In the dark, intracellular injection of cGMP into a gecko photoreceptor caused a long-lasting depolarization. An intense light flash given during the depolarization phase repolarized the cell with a s...

Journal: :Respiratory Research 2004
Robert A Clayton Colin AJ Dick Alison Mackenzie Michiaki Nagasawa Deirdre Galbraith Stuart F Hastings Simon J MacKenzie

BACKGROUND The anti-inflammatory effects of the selective phosphodiesterase (PDE) inhibitors cilostazol (PDE 3), RO 20-1724 (PDE 4) and sildenafil (PDE 5) were examined in a murine model of allergic asthma. These compounds were used alone and in combination to determine any potential synergism, with dexamethasone included as a positive control. METHODS Control and ovalbumin sensitised Balb/C ...

Journal: :Carcinogenesis 2007
Weiming Ouyang Yu Hu Jingxia Li Min Ding Yongju Lu Dongyun Zhang Yan Yan Lun Song Qingshan Qu Dhimant Desai Shantu Amin Chuanshu Huang

Nuclear factor of activated T cell (NFAT)-3 is a member of the transcription factor NFAT family, which has been demonstrated to be responsible for the up-regulation of the pro-inflammatory cytokine tumor necrosis factor (TNF) in the immune system. Our most recent studies have also shown that TNF is able to induce cell transformation in mouse epidermal Cl41 cells by induction of cyclooxygenase-2...

Journal: :Journal of leukocyte biology 1999
A Zakaroff-Girard S El Bawab G Némoz M Lagarde A F Prigent

We have previously shown that mitogenic activation of human PBMC rapidly increases both the intracellular phosphatidic acid (PA) level and cyclic nucleotide phosphodiesterase (PDE) activity, with time-course responses, suggesting a causative relationship between the two events. PA also directly stimulated cAMP-PDE activity in acellular systems. Thus the mitogenic properties of PA night be due t...

ژورنال: :فیزیک زمین و فضا 2014
مهدی گلی مهدی نجفی علمداری

اثر جاذبی توپوگرافی به منزله یک مولفه کلیدی، در مدل سازی میدان گرانی زمین نقش مهمی ایفا می کند. محاسبه اثر توپوگرافی به کمک مدل های رقومی زمین که در دستگاه مختصات (گاوسی) ژئودتیکی داده می شوند، صورت می گیرد. معمولا برای محاسبه این اثر از تقریب کروی انتگرال نیوتن استفاده می شود. این تحقیق به تقریب بیضوی پتانسیل جاذبی ناشی از توپوگرافی و گرادیان ارتفاعی آن اختصاص دارد. در این مقاله روابط کاملی بر...

پایان نامه :وزارت علوم، تحقیقات و فناوری - دانشگاه بناب - دانشکده علوم ریاضی 1391

در این پایان نامه ابتدا یک معادله pde را به یک معادله ode تبدیل می کنیم بعد به تحلیل جواب های معادله ode می پردازیم و این کار در 101 صفحه گردآوری شده و بسیاری از کارهای برنامه نویسی این کار توسط نرم افزار میپل و متمتیکا انحام شده است.

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