OBJECTIVES This study examined the relationship between stress, self-efficacy, self-medication, and pharmacological neuroenhancement (PNE) in the Swiss general population. METHODS Using the largest Swiss Internet panel, a sample of 10,171 employees and students (unweighted N=10,084) aged 15-74 years was recruited and asked to complete a self-administered online survey. The data were weighted ...

It is an important step in deign under uncertainty to select an appropriate uncertainty propagation (UP) method considering the characteristics of the engineering systems at hand, the required level of UP associated with the probabilistic design scenario, and the required accuracy and efficiency levels. Many uncertainty propagation methods have been developed in various fields, however, there i...

Effects of p.o. administration of sulfolithocholic acid disodium salt (SLCNa) and lithocholic acid sodium salt (LCNa) on N-methyl-N-nitrosourea (MNU)-induced colonic tumorigenesis were studied in conventional rats. Female F344 rats received either 0.5 ml of distilled water (DW) alone or DW containing 2.5 mg of MNU twice in 1 wk intrarectally. Then rats were fed freely on a basal diet (PCE-2) or...

Podocyte injury contributes to renal damage and, eventually, to the occurrence of proteinuria in diabetic nephropathy. The aim of the present study was to investigate the effect of an ethanol extract from Rhizoma Polygonum cuspidatum (P. cuspidatum) on proteinuria and podocyte injury, and elucidate the underlying mechanism for streptozotocin (STZ)‑induced diabetic nephropathy. The protective ef...

BACKGROUND Prior studies of prenatal exposure to tetrachloroethylene (PCE) have shown mixed results regarding its effect on birth weight and gestational age. OBJECTIVES In this retrospective cohort study we examined whether PCE contamination of public drinking-water supplies in Massachusetts influenced the birth weight and gestational duration of children whose mothers were exposed before the...

The aim of the present study was to investigate whether ethanol extracts of Psoralea corylifolia L. (PCE) and its active component protect against bone loss in ovariectomised rats. We screened oestrogenic activities of the main extract fractions using in vitro assays and identified bakuchiol as the most active oestrogenic component by HPLC and LC/MS, and then demonstrated that bakuchiol had str...

The properties of perovskite solar cells (PSCs) fabricated using various solvents was studied. The devices had an indium tin oxide (ITO)/poly(3,4-ethylenedioxythiophene): poly(styrenesulfonate) (PEDOT:PSS)/CH3NH3PbI3 (fabricated by using various solvents)/fullerene (C60)/bathocuproine (BCP)/silver (Ag) structure. The solvents used were dimethylformamide (DMF), γ-butyrolactone (GBL), dimethyl su...

The objective of this note is to show how one can combine Polynomial Chaos Expansions (PCE) and adjoint theory to efficiently obtain sensitivities for robust optimal control. A non-intrusive PCE method is used to analyze the constraint equations for the state (which depends on uncertain inputs), namely the governing equations of the dynamical system. Adjoint solutions are constructed for each o...

Fastidious anaerobic bacteria play critical roles in environmental bioremediation of halogenated compounds. However, their characterization and application have been largely impeded by difficulties in growing them in pure culture. Thus far, no pure culture has been reported to respire on the notorious polychlorinated biphenyls (PCBs), and functional genes responsible for PCB detoxification rema...

El cómputo de rutas en Internet se ha vuelto una tarea compleja y costosa. La arquitectura PCE (Path Computation Element) proporciona la funcionalidad necesaria para el cómputo de rutas interdominio en redes MPLS (Multiprotocol Label Switching) y GMPLS (Generalized Multiprotocol Label Switching). En este escenario, el cálculo de rutas interdominio se lleva a cabo mediante la cooperación entre P...