primary cutaneous anaplastic large cell lymphoma is a t-cell malignancy with atypical cd30 positive lymphocytes. pseudoepitheliomatous hyperplasia is an uncommon finding in primary cutaneous anaplastic large cell lymphoma, and may mimic squamous cell carcinoma as pseudomalignancy. careful attention of a pathologist to correct diagnosis of pseudoepitheliomatous hyperplasia and its underlying cau...

1 MD. Pathologist; Erasto Gaertner Hospital, Curitiba, Paraná, Brazil. 2 PhD in Pathology; Preceptor of the Medical Residency at Erasto Gaertner Hospital, Curitiba, Paraná, Brazil. 3 MSc in Pathology; Pathologist at the Erasto Gaertner Hospital, Curitiba, Paraná, Brazil. 4 Medical Student; Federal University of Paraná, Curitiba, Paraná, Brazil. 5 PhD in Pathology; Department Head Erasto Gaertne...

The role of adhesion molecules is very important both in the activation of carcinogenesis and in the differentiation of subtypes of breast carcinoma, aiding in diagnosis, prognosis and therapeutic choice in these tumors. Therefore, understanding the functions and interrelationships among these molecules is crucial to the pathologist, who often uses these factors as a resource to differentiate t...

This is a state-of-the-art review of the molecular genetics of pancreatic neoplasms. Although understanding of the molecular features underlying pancreatic neoplasms is still in its infancy, a strong emphasis on the relevance of these findings for the practicing surgical pathologist is provided. The application of molecular techniques has yielded a wealth of information that may soon enhance di...