Though lithium-induced neurotoxicity usually occurs when serum lithium exceeds 2.0 mEq/1, reports document its occurrence with serum lithium within the therapeutic range (Strayhorn and Nash 1977, Hansen and Amidsen, 1978, Speirs and Hirsch 1978, West and Meltzer 1979). Neurotoxicity has even been described with serum lithium between 0.4 and 0.5 mEq/1 (Hansen and Amidsen 1978). Such may best be ...

complaining of pain in the abdomen. During the previous four months his appetite had been poor and he had lost some weight. His bowel movements had been regular, except for an occasional attack of diarrhea. There had been no nausea or vomiting. Four days before admission he complained of dull steady pain in the epigastrium and both flanks. Simultaneously he became constipated and was unable to ...

OBJECTIVE To review the clinical features, neurobiological correlates and treatment of pathological laughing and crying. METHOD Selective literature review. RESULTS Attacks of involuntary, irresistible laughing or crying have long been recognised as sequelae of brain damage. There is controversy about the clinical features of these attacks, the stimuli that provoke them and their relation t...

In recent years, autoimmune pancreatitis has been established as a special type of chronic pancreatitis. It is characterized by its histopathological and immunological features. The morphological hallmarks are periductal infiltration by lymphocytes and plasma cells and granulocytic epithelial lesions with consequent destruction of the duct epithelium and venulitis. Autoimmune pancreatitis has t...

Pathological findings are described in four cases of a new aminoaciduria in which homocystine is excreted in the urine. All the patients were mentally retarded children. Three of them presented diagnostic features of Marfan's syndrome. Necropsy on one case and biopsy findings in the others are described. Fatty change occurs in the liver. The most striking lesions are vascular. Metachromatic med...

Plant hormones play important roles in regulating developmental processes and signalling networks involved in plant responses to a wide range of biotic and abiotic stresses. Salicylic acid (SA), jasmonates (JA) and ethylene (ET) are well known to play crucial roles in plant disease and pest resistance. However, the roles of other hormones such as abscisic acid (ABA), auxin, gibberellin (GA), cy...

present ones. The plates cover a wide lange of subjects of both medical and surgical inteiest, and maintain an uniformly high standaid. Among the best are those illustrating diseases of the larynx and pharynx, the latter including one of a gangrenous condition so familiar as a complication of kala-azar in Calcutta, lhat 01 tubercle of the lcidney and bladder is also veiy good. Various diseases ...

The pathological potential of glial cells was recognized already by Rudolf Virchow, Santiago Ramon y Cajal and Pio Del Rio-Ortega. Many functions and roles performed by astroglia in the healthy brain determine their involvement in brain diseases; as indeed any kind of brain insult does affect astrocytes, and their performance in pathological conditions, to a very large extent, determines the su...