Specialist and generalist pathogens may exert different costs on their hosts; thereby altering the way hosts cope with environmental variation. We examined how pathogen-challenge alters the environmental conditions that maximize host performance by simultaneously varying temperature and nutrition (protein to carbohydrate ratio; P:C) after exposure to two baculoviruses; one that is specific to t...

Female genital tract infections are major public health problems, with considerable economic consequences. Drugs like metronidazole and clindamycin unable to control the growth of vaginal infection completely, which requires alternate novel treatment strategies. Some herbal antimicrobial agents reported inhibit infection. Boerhaavia diffusa andAzadirachta indica such herbs antimicrobial, antiox...

Respiratory pathogens such as influenza and SARS-CoV-2 can cause severe lung infections leading to acute respiratory distress syndrome (ARDS). The pathophysiology of ARDS includes an excessive host immune response, epithelial endothelial cell death loss the barrier integrity, culminating in pulmonary oedema failure. Traditional approaches for treatment include drugs that exert direct anti-patho...

Significance The functional diversity of MAPKs is dependent on differential selection substrates for phosphorylation. Nevertheless, the mechanisms assisting to maintain substrate specificity in plants are not known. Our study shows that WRKY33, a pathogen-responsive MPK3/6 substrate, SUMOylated response pathogen-associated molecular patterns and pathogen signals. SUMOylation mediates WRKY33 pho...

Food neophobia and disgust are commonly thought to be linked, but this hypothesis is typically implicitly assumed rather than directly tested. Evidence for the connection has been based on conceptually and empirically unsound measures of disgust, unpublished research, and indirect findings. This study (N = 283) provides the first direct evidence of a relationship between trait-level food neopho...

As tick-borne diseases are on the rise, an international effort resulted in the sequence and assembly of the first genome of a tick vector. This result promotes research on comparative, functional and evolutionary genomics and the study of tick-host-pathogen interactions to improve human, animal and ecosystem health on a global scale.