Rho family GTPases are primary mediators of cytoskeletal reorganization, although they have also been reported to regulate cell secretion. Yet, the extent to which Rho family GTPases are activated by secretory stimuli in neural and neuroendocrine cells remains unknown. In bovine adrenal chromaffin cells, we found Rac1, but not Cdc42, to be rapidly and selectively activated by secretory stimuli ...

Chest tube is a flexible plastic tube used to discharge secretion in the cavity between the lungs and chest named pleural cavity. Normally, there is a small amount of fluid in the cavity between the lungs and chest; This fluid helps the movement of lungs during breathing without abrasion. Entrance of bit of air, blood or pus because injury in the pleural cavity can prevent the lungs from fully ...

The virulence factors of pathogenic bacteria are major secretory proteins that are directly linked to their pathogenicity. These secretory proteins are translocated across the membranes of bacterial cells by translocase nanomachines, which consists of integral membrane proteins. The periodontal pathogen, Porphyromonas gingivalis, secretes trypsin-like proteases(gingipains)either as a large comp...

The Ysa type III secretion (T3S) system enhances gastrointestinal infection by Yersinia enterocolitica bv. 1B. One effector protein targeted into host cells is YspP, a protein tyrosine phosphatase. It was determined in this study that the secretion of YspP requires a chaperone, SycP. Genetic analysis showed that deletion of sycP completely abolished the secretion of YspP without affecting the s...

background regarding the process of increasing the divorce rate in recent years and youth population, the awareness among the youth, especially the university students, about marriage and criteria of choosing a right partner for proper planning to preserve family is of great importance. objectives the aim of this study was to investigate the viewpoint of unmarried students of semnan university ...

Background: Pathogenic yersiniae (Y. pestis, Y. pseudotuberculosis, Y. enterocolitica) share a virulence plasmid encoding a type three secretion system (T3SS). This T3SS comprises more than 40 constituents. Among these are the transport substrates called Yops (Yersinia outer proteins), the specific Yop chaperones (Sycs), and the Ysc (Yop secretion) proteins which form the transport machinery. T...

The aim of this study is to present a psychometrically sound instrument to assess intimate partner violence offenders’ responsibility attributions: the Intimate Partner Violence Responsibility Attribution Scale. The scale was administrated to 423 adult male intimate partner violence offenders court-mandated to a community-based intervention program. A three factor structure (responsibility attr...