Parkinson's disease (PD) is the most common form of Parkinsonism, a group neurological disorders, and second neurodegenerative disorder. More than six million people worldwide are affected by PD. Over past two decades, Virtual Reality (VR) technology commercial gaming devices used as intervention tools for rehabilitation. The aim this systematic review to study efficacy rehabilitation in VR env...

Directing stem cells and progenitors towards neuronal differentiation – implications for experimental therapies for Parkinson’s disease Anke Brederlau Institute of Biomedicine, Department of Medical Chemistry and Cell Biology, Sahlgrenska Academy at Gothenburg University, Sweden. The insight that stemand progenitor-cells contribute to replacement of nerve cells in the adult central nervous syst...

English) A global mapping of early stage medical technology companies active in the neurology field has been implemented. The companies have emerging products and have undergone an evaluation by clinicians concerning the ability to provide clinical value for Swedish health care. The evaluation process has been executed by discussion with neurologists and neurosurgeons in combination with a lite...

Research of the past 25 years has shown that astrocytes do more than participating and building up the blood-brain barrier and detoxify the active synapse by reuptake of neurotransmitters and ions. Indeed, astrocytes express neurotransmitter receptors and, as a consequence, respond to stimuli. Within the tripartite synapse, the astrocytes owe more and more importance. Besides the functional asp...

The cable equation describes the voltage in a straight cylindrical cable, and this model has been employed to model electrical potential in dendrites and axons. However, sometimes this equation might give incorrect predictions for some realistic geometries, in particular when the radius of the cable changes significantly. Cables with a nonconstant radius are important for some phenomena, for ex...

Abstract Introduction Sleep disturbance in patients with Parkinson's disease (PD) is highly prevalent. PD the second most common progressive neurodegenerative disease, affecting about 1% of people over 60 years. Little it's said sleep disorders this which are very frequent and frequently underdiagnosed. In Mexico, there not a lot studies on their population. University Hospital Dr. José E. Gonz...

Dopamine (DA) is a major neurotransmitter important for neuroendocrine control and recent studies have described genomic signaling pathways activated and inhibited by DA agonists and antagonists in the goldfish brain. Here we perform a meta-type analysis using microarray datasets from experiments conducted with female goldfish to characterize the gene expression responses that underlie dopamine...

Parkinson's disease (PD) and essential tremor (ET) are characterized with motor dysfunctions. Motor circuit dysfunctions can be complementarily investigated by paired associative stimulation (PAS)-induced long-term potentiation (LTP)-like plasticity and diffusion tensor imaging (DTI) of the corticospinal tract (CST). Three groups of twelve subjects with moderate severity PD, ET with intention t...