نتایج جستجو برای: paraoxonase

تعداد نتایج: 2123  

Journal: :The Eurasian journal of medicine 2012
Serap Yildirim Songul Doganay Abdulkadir Yildirim Osman Enver Aydin Akar Karakoc Esra Laloglu

OBJECTIVE This study investigated changes in serum oxidative stress parameters in burn cases compared to healthy controls. MATERIALS AND METHODS This study was performed in 41 burn patients with mild to severe thermal burn injuries and 38 healthy volunteers. The burn cases were selected from patients who were hospitalized in the burn unit for the treatment of second- and third-degree burns. M...

2012
Necat Yilmaz

Homocysteine (Hcy) is an accepted independent risk factor for several major pathologies including cardiovascular disease, birth defects, osteoporosis, Alzheimer's disease, and renal failure. Interestingly, many of the pathologies associated with homocysteine are also linked to oxidative stress. The enzyme paraoxonase (PON1) - so named because of its ability to hydrolyse the toxic metabolite of ...

Journal: :Stroke 2002
M Yamada N Sodeyama Y Itoh E Otomo M Matsushita H Mizusawa

BACKGROUND AND PURPOSE Both cerebral amyloid angiopathy (CAA) and paraoxonase have been reported to be related to lipid metabolism and atherosclerosis. We investigated whether the paraoxonase gene (PON1) polymorphism and atherosclerosis are associated with risk of CAA. METHODS Associations of the PON1 polymorphism and atherosclerosis of the aorta and coronary and cerebral arteries with the se...

2013
Hamit Yasar Ellidag Esin Eren Ozgur Aydin Mustafa Yıldırım Cem Sezer Necat Yilmaz

OBJECTIVE To investigate the status of the oxidant/antioxidant balance in patients with multiple myeloma compared to healthy controls. MATERIALS AND METHODS This study was conducted on 40 multiple myeloma patients and 40 healthy controls of matched age and sex. Serum total thiol, oxidative stress index (OSI), total oxidant status (TOS), and total antioxidant status (TAS) were measured using c...

Journal: :Arteriosclerosis, thrombosis, and vascular biology 2001
S T Reddy D J Wadleigh V Grijalva C Ng S Hama A Gangopadhyay D M Shih A J Lusis M Navab A M Fogelman

Paraoxonase-1 (PON1) is a secreted protein associated primarily with high density lipoprotein (HDL) and participates in the prevention of low density lipoprotein (LDL) oxidation. Two other paraoxonase (PON) family members, namely, PON2 and PON3, have been identified. In this study, we report the cloning and characterization of the human PON3 gene from HepG2 cells. Tissue Northern analysis ident...

Journal: :Turkish journal of internal medicine 2022

Background The aim of the present study was estimation serum paraoxonase (PON1) activity in severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).
 Material and Methods In this cross-sectional we estimated 73 patients with SARS-CoV-2 infection healthy controls.
 Results results showed that PON1 significantly decreased (1.30±0.55 kU/L) than controls (1.913±0.48 kU/L, p

2008
Joseph Loscalzo

Organophosphates were first synthesized in the 1930s as insecticides1 and were subsequently shown to have direct neurotoxic effects in mammals, as well. The neurotoxicity is derived from their ability to inhibit acetylcholinesterase by covalently modifying the active-site serine group in the enzyme. Mazur2 first demonstrated the presence of an organophosphate-hydrolyzing enzyme in mammalian tis...

نمودار تعداد نتایج جستجو در هر سال

با کلیک روی نمودار نتایج را به سال انتشار فیلتر کنید