Paraneoplastic syndromes (PS) are the consequences of hormones or immune cross-reactivity produced by a tumor. Nephrotic syndrome (NS) is an extremely rare PS resulting from thymoma. Here, case 55-year-old woman presenting progressive generalized edema and foamy urine reported. The patient’s chest CT scan showed anterior mediastinum with intramural punctate calcification size 8.6x7.0x10.2 cm. w...

Gastric adenocarcinoma developing concomitantly with a lymphoma is rare. Furthermore, B-cell lymphoma, originating from lymph nodes, with eosinophilia is extremely rare. We report here a case with a synchronous diffuse large B-cell lymphoma (DLBCL) and an early adenocarcinoma of the stomach. In addition, this case seemed to be associated with paraneoplastic cutaneous vasculitis caused by hypere...

PURPOSE OF REVIEW The most relevant advances in the field of paraneoplastic neurological syndromes are described, with special emphasis on particular clinical-immunological associations and practical issues for the diagnosis and treatment of these disorders. RECENT FINDINGS Paraneoplastic neurological syndromes may present with classical neurological symptoms or less frequently with symptoms ...

BACKGROUND paraneoplastic neurological syndromes (PNS) almost invariably predate detection of the malignancy. Screening for tumours is important in PNS as the tumour directly affects prognosis and treatment and should be performed as soon as possible. OBJECTIVES an overview of the screening of tumours related to classical PNS is given. Small cell lung cancer, thymoma, breast cancer, ovarian c...

Hypertrophic osteoarthropathy is a paraneoplastic syndrome most often found in non-small cell lung cancer. Diagnosis is confirmed by the presence of clubbing on physical examination and periostitis on bone scintigram, and the syndrome generally resolves with treatment of the underlying malignancy. This article presents a case study and describes symptom management options, including nonsteroida...

Complex regional pain syndrome type I (CRPS-I) is infrequently associated with various malignancies, and may lead to severe pain in already debilitated patients. The causal relationship between CRPS-I and paraneoplastic syndrome, controversies in diagnosis and treatment, and new treatment modalities are presented.

Necrolytic migratory erythema is an obligatory paraneoplastic syndrome. Here we describe a patient with a neuroendocrine tumor of probably pancreatic origin. She developed the typical skin lesions under chemotherapy with temozolomide and capecitabine.

INTRODUCTION Opsoclonus-myoclonus syndrome is a rare autoimmune syndrome usually seen in children and very rarely in adults. It typically presents with a triad of opsoclonus, myoclonus and ataxia, and is most often associated with a tumor or after an infection or vaccination. Around half of all adult cases are paraneoplastic in origin, and isolated case reports include associations with lung, b...

Background: The increase in the incidence of malignancies globally, and usage frequency types new anti-cancer drugs, have made onconephrology more important our clinical practice. Paraneoplastic glomerulonephritis constitutes an part this approach as well. Purpose: association AML-nephrotic syndrome is relatively less defined literature compared to other hematological malignancies. Case present...

Paraneoplastic syndromes are disorders associated with cancer but without a direct effect of the tumor mass or its metastases on the nervous system. Small cell carcinoma of lung associated with paraneoplastic sensory neuronopathy and/or paraneoplastic encephalomyelitis with the presence of anti-Hu antibodies has been termed "anti-Hu syndrome." Anti-Hu associated PSN-PEM is an immune disorder in...