background: chlorotoxin is a 36-amino acid peptide found in the venom of the leiurus quinquestriatus which blocks small-conductance chloride channels. chlorotoxin binds preferentially to glioma cells that allow development of new methods for the treatment and diagnosis of several types of cancer. thus chlorotoxin derivative was labeled with 131i for further investigation. materials and methods:...

objective(s):human cytomegalovirus (hcmv) remains a major morbidity and mortality cause in immuno suppressed patients. therefore, significant effort has been made towards the development of a vaccine. in this study, the expression of the pp65 and gb fusion peptides and fc domain of mouse igg2a as a novel delivery system for selective uptake of antigens by antigen-presenting cells (apcs) in pich...

the rotavirus nonstructural protein 4 (nsp4), is a multi functional protein that play key role in both viral morphogenesis and cytopathic effect associated with cell death. however, the complete biological effect of nsp4 remains to be clarified. since to obtain further knowledge about this protein there is a need for recognizing antibody and there is no commercial antibody against this protein...

interferon is a protein secreted by eucaryotic cells following stimulation by viruses, bacteria, and many other immunogenes. recent medical studies indicate that interferons have effective role in the treatment of virus infections, immunodeficiency and certain types of cancer such as hairy cell leukaemia (hcl). the aim of the present study is to apply yeast strain for secreting human ifnα2b fol...

objective: dna vaccines have been widely used to develop immunity against various pathogens including parasites and viruses. the potential of dna vaccine to induce an effective immune response is related to the expression levels of the encoded protein in eukaryotic cells. therefore, optimization of plasmid dna delivery system is a major concern in protein expression in order to make an efficien...

El divorcio o la separación conyugal implica cambios en estructura de las familias y los arreglos convivencia que han estado marcados por sesgos género. Reconociendo importancia implicación del padre el desarrollo hijos factor protector supone estos escenarios, se realizó una revisión sistemática literatura con objetivo conocer variables vinculan a padres no residentes. Aplicando criterios búsq...

Objetivo: Analizar los significados atribuidos a la paternidad por hombres al ser padres primera vez.Participantes y Método: Investigación cualitativa de diseño Hermenéutico-Dialéctico. La recolección datos fue realizada través entrevistas en profundidad madres (10 cada uno), niños/as mayores 12 meses. El análisis información se llevó cabo del discurso participantes su articulación con el conte...