نتایج جستجو برای: p7

تعداد نتایج: 1741  

2013
Natassya M. Noor Kjeld Møllgård Benjamin J. Wheaton David L. Steer Jessie S. Truettner Katarzyna M. Dziegielewska W. Dalton Dietrich A. Ian Smith Norman R. Saunders

Ubiquitin, an 8.5 kDa protein associated with the proteasome degradation pathway has been recently identified as differentially expressed in segment of cord caudal to site of injury in developing spinal cord. Here we describe ubiquitin expression and cellular distribution in spinal cord up to postnatal day P35 in control opossums (Monodelphis domestica) and in response to complete spinal transe...

Journal: :Computational biology and chemistry 2014
Leon Bichmann Yi-Ting Wang Wolfgang B. Fischer

Protein p7 of HCV is a 63 amino acid channel forming membrane protein essential for the progression of viral infection. With this momentousness, p7 emerges as an important target for antiviral therapy. A series of small molecule drugs, such as amantadine, rimantadine, amiloride, hexamethylene amiloride, NN-DNJ and BIT225 have been found to affect the channel activity. These compounds are docked...

Journal: :Stroke 2012
Christiane Charriaut-Marlangue Philippe Bonnin Abdallah Gharib Pierre-Louis Leger Sonia Villapol Marc Pocard Pierre Gressens Sylvain Renolleau Olivier Baud

BACKGROUND AND PURPOSE We recently demonstrated that endogenous nitric oxide (NO) modulates collateral blood flow in a neonatal stroke model in rats. The inhalation of NO (iNO) has been found to be neuroprotective after ischemic brain damage in adults. Our objective was to examine whether iNO could modify cerebral blood flow during ischemia-reperfusion and reduce lesions in the developing brain...

2017
Roser Urreizti Anna Maria Cueto-Gonzalez Héctor Franco-Valls Sílvia Mort-Farre Neus Roca-Ayats Julia Ponomarenko Luca Cozzuto Carlos Company Mattia Bosio Stephan Ossowski Magda Montfort Jochen Hecht Eduardo F. Tizzano Bru Cormand Lluïsa Vilageliu John M. Opitz Giovanni Neri Daniel Grinberg Susana Balcells

Opitz trigonocephaly C syndrome (OTCS) is a rare genetic disorder characterized by craniofacial anomalies, variable intellectual and psychomotor disability, and variable cardiac defects with a high mortality rate. Different patterns of inheritance and genetic heterogeneity are known in this syndrome. Whole exome and genome sequencing of a 19-year-old girl (P7), initially diagnosed with OTCS, re...

2013
Bernardo Neme Ide Lázaro Alessandro Soares Nunes René Brenzikofer Denise Vaz Macedo

The purpose of this study was to observe the time course of muscle damage and inflammatory responses following an eccentric overload resistance-training (EO) program. 3 females (23.8 ± 2.6 years; 70.9 ± 12.7 kg; 1.6 ± 0.08 m) and 5 males (23.8 ± 2.6 years; 75.1 ± 11.2 kg; 1.8 ± 0.1 m) underwent thirteen training sessions (4 × 8-10 eccentric-only repetitions-80% of eccentric 1RM, one-minute rest...

Journal: :American journal of physiology. Lung cellular and molecular physiology 2006
Richard L Auten Michael A O'Reilly Tim D Oury Eva Nozik-Grayck Mary H Whorton

Transgenic (TG) human (h) extracellular superoxide dismutase (EC-SOD) targeted to type II cells protects postnatal newborn mouse lung development against hyperoxia by unknown mechanisms. Because alveolar development depends on timely proliferation of type II epithelium and differentiation to type I epithelium, we measured proliferation in bronchiolar and alveolar (surfactant protein C-positive)...

Journal: :Development 2013
Paul J Minor Ting-Fang He Chang Ho Sohn Anand R Asthagiri Paul W Sternberg

The interpretation of extracellular cues leading to the polarization of intracellular components and asymmetric cell divisions is a fundamental part of metazoan organogenesis. The Caenorhabditis elegans vulva, with its invariant cell lineage and interaction of multiple cell signaling pathways, provides an excellent model for the study of cell polarity within an organized epithelial tissue. Here...

Journal: :Stem cells and development 2013
Oksana Forostyak Nataliya Romanyuk Alexei Verkhratsky Eva Sykova Govindan Dayanithi

Human embryonic stem cell-derived neural precursors (hESC NPs) are considered to be a promising tool for cell-based therapy in central nervous system injuries and neurodegenerative diseases. The Ca(2+) ion is an important intracellular messenger essential for the regulation of various cellular functions. We investigated the role and physiology of Ca(2+) signaling to characterize the functional ...

Journal: :Plantropica: journal of agricultural science 2022

The high population and the lack of productive land in Indonesia cause environmental problems caused by pollution waste. Urban farming could be a solution to provide food needs can also improve urban conditions. Lettuce are suitable for cultivation areas, taste benefits make lettuce have good prospects. Reusing waste such as roasted husks goat manure fertilizer beneficial environment. This rese...

Journal: :International Journal of Molecular Sciences 2021

Kaempferol is a polyphenol found in variety of plants. exerts antitumor properties by affecting proliferation and apoptosis cancer cells. We investigated whether kaempferol its glycoside derivatives—kaempferol 3-O-[(6-O-E-caffeoyl)-?-D-glucopyranosyl-(1?2)]-?-D-galactopyranoside-7-O-?-D-glucuropyranoside (P2), 3-O-[(6-O-E-p-coumaroyl)-?-D-glucopyranosyl-(1?2)]-?-D-galactopyranoside-7-O-?-D-gluc...

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